Results 31 to 40 of about 430,056 (186)

A rare cause of recurrent hypersomnia- Klein-Levin syndrome

Manipal Journal of Medical Sciences, 2022
Recurrent episodes of severe hypersomnia coupled with cognitive and behavioral abnormalities like disorientation, apathy, derealization, compulsive eating and hypersexuality are hallmarks of unusual sleep disease known as Klein-Levin syndrome. We hereby discuss a 46-year-old gentleman who came with recurrent episode of loss of muscle tone, was ...
MOHAMMED KHALID, Tariq karim, Waqas Anwar   +2 more
openaire   +1 more source

Low-dose clozapine monotherapy for recurring episodes of depression, hypersomnia and behavioural disturbances: a case report

, 2011
Havaki-Kontaxaki BJ, Ferentinos PP, Kontaxakis VP, Kontaxaki M-I V, Geronikola X, Armeniakos I, Papadimitriou GN. Low-dose clozapine monotherapy for recurring episodes of depression, hypersomnia and behavioural disturbances: a case report.Case Report: We
George N. Papadimitriou, Maria-Irini V. Kontaxaki, Ioannis Armeniakos, Xenia Geronikola, Vassilis P. Kontaxakis, Beata J. Havaki-Kontaxaki, Panagiotis P. Ferentinos   +6 more
core   +3 more sources

Retrospective Analysis of Patients Undergoing Video-EEG Monitoring

Archives of Epilepsy, 2023
Objective:Video-electroencephalography (EEG) monitoring (VEM) is an essential tool in diagnosing and treating epilepsy as it enables real-time monitoring and recording of electrical activity in the brain.
Azer Memmedov, Ceren Aliş, Şakir Delil, Taner Tanrıverdi, Seher Naz Yeni   +4 more
doaj   +1 more source

SORN : a self-organizing recurrent neural network [PDF]

, 2009
Understanding the dynamics of recurrent neural networks is crucial for explaining how the brain processes information. In the neocortex, a range of different plasticity mechanisms are shaping recurrent networks into effective information processing ...
Pipa, Gordon, Andreea Lazar, Triesch, Jochen, Lazar, Andreea, Gordon Pipa, Jochen Triesch   +5 more
core   +1 more source

Sleeping beauty syndrome: A case report and review of female cases reported from India

Indian Journal of Psychological Medicine, 2017
Kleine–Levin syndrome (KLS), also called “Sleeping beauty syndrome” is a rare, disorder predominantly reported in adolescent males, characterized by recurrent episodes of hypersomnia and to various degrees, hyperphagia, cognitive disturbances, and ...
Naresh Nebhinani, Navratan Suthar
doaj   +1 more source

Atypical Kleine–Levin syndrome: An elusive entity?

Journal of Family Medicine and Primary Care, 2017
Kleine–Levin syndrome (KLS) is a rare disorder (around 1.5 cases per million population), often presenting with triad of recurrent episodes of hypersomnia, hyperphagia, and hypersexuality.
Swarndeep Singh, Saurabh Kumar, Rohit Verma, Nand Kumar   +3 more
doaj   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

Monozygotic twins concordant for Kleine-Levin syndrome

BMC Neurology, 2012
Background Kleine-Levin syndrome is a rare sleep disorder of unknown etiology. It is characterized by intermittent periods of excessive sleepiness, cognitive disturbances and behavioral abnormalities.
Ueno Taro, Fukuhara Akira, Ikegami Azusa, Ohishi Fumihiro, Kume Kazuhiko   +4 more
doaj   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Long-Term Treatment of Narcolepsy and Idiopathic Hypersomnia with Low-Sodium Oxybate

, 2023
Logan D Schneider,1 Anne Marie Morse,2 Michael J Strunc,3 Joyce K Lee-Iannotti,4 Richard K Bogan5 1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; 2Janet Weis Children’s Hospital, Geisinger ...
Lee-Iannotti JK, Morse AM, Schneider LD, Strunc MJ, Bogan RK   +4 more
core