Results 211 to 220 of about 834,982 (344)

TGF‐β1 Directly Sensitizes Capsaicin‐Sensitive Lung Vagal Neurons to Promote Airway Hypersensitivity

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Transforming growth factor‐β1 (TGF‐β1) is a pleiotropic cytokine implicated in the pathogenesis of inflammatory airway diseases such as asthma. Airway hypersensitivity (AHS), arising from sensitization of capsaicin‐sensitive lung vagal (CSLV) afferents, is a hallmark of these airway diseases.
Yueh‐Yin Chen   +2 more
wiley   +1 more source

Associations of Outdoor Air Pollution With Incidence of Cancers Other Than Lung Cancer in a Large US Prospective Cohort

open access: yesInternational Journal of Cancer, Volume 159, Issue 6, Page 1440-1454, 15 September 2026.
Associations between outdoor air pollution and cancers other than lung cancer remain unclear, particularly in the context of tobacco use. Here, the authors assessed possible links between ambient air pollutant exposure and incidence of 20 non‐lung cancers among adults followed over a 25‐year period in the United States.
W. Ryan Diver   +4 more
wiley   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei   +18 more
wiley   +1 more source

Placental-Derived Connective Tissue Matrix Mediates Murine Recurrent Laryngeal Nerve Regeneration. [PDF]

open access: yesLaryngoscope
Anekal S   +7 more
europepmc   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1368-1381, September 2026.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya   +2 more
wiley   +1 more source

Extent of Lymph Node Dissection for cStage I Siewert Type I/II Cancers Based on Lymph Node Metastasis Risk Stratification

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1478-1485, September 2026.
ABSTRACT Aim The optimal surgical strategy and extent of lymph node (LN) dissection for clinical Stage I (cStage I) adenocarcinoma of the esophagogastric junction (AEG) remain controversial. This study aimed to evaluate surgical outcomes and clarify the prevalence and distribution of LN metastasis according to tumor characteristics in cStage I Siewert ...
Masayoshi Terayama   +9 more
wiley   +1 more source

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