Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Molecular, Biochemical, and Bioimaging Markers of MEN Syndromes. [PDF]
Petranović Ovčariček P +6 more
europepmc +1 more source
NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi +11 more
wiley +1 more source
Advances in Chinese herbal medicine for diabetic wound treatment: from tradition to innovation. [PDF]
Hong Z +6 more
europepmc +1 more source
Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk +6 more
wiley +1 more source
Exploring immune-endothelial interactions in neuroinflammation and vascular dysfunction. [PDF]
Wang Z +5 more
europepmc +1 more source
Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu +7 more
wiley +1 more source
Mathematical foundations of life, mind and all emergent phenomena. [PDF]
Werbos PJ.
europepmc +1 more source
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang +4 more
wiley +1 more source
The Genomic Patterns of Well-Differentiated Pancreatic Neuroendocrine Tumors (NETs) Identify Sub-Sets for Rational Therapeutic Targeting. [PDF]
Voutsadakis IA.
europepmc +1 more source

