Results 91 to 100 of about 92,175 (266)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Lipschitz Recurrent Neural Networks

open access: yes, 2020
Published as a conference paper at ICLR ...
N. Benjamin Erichson   +4 more
openaire   +3 more sources

Recurrent Neural Networks as Electrical Networks, a Formalization

open access: yes, 2023
Since the 1980s, and particularly with the Hopfield model, recurrent neural networks or RNN became a topic of great interest. The first works of neural networks consisted of simple systems of a few neurons that were commonly simulated through analogue electronic circuits.
Mariano Caruso, Cecilia Jarne
openaire   +2 more sources

Learning compact recurrent neural networks [PDF]

open access: yes2016 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2016
Recurrent neural networks (RNNs), including long short-term memory (LSTM) RNNs, have produced state-of-the-art results on a variety of speech recognition tasks. However, these models are often too large in size for deployment on mobile devices with memory and latency constraints. In this work, we study mechanisms for learning compact RNNs and LSTMs via
Zhiyun Lu   +2 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

EMP response modeling of TVS based on the recurrent neural network

open access: yesJournal of Hebei University of Science and Technology, 2015
Due to the larger workload in the implementation process and the poor consistence between the test results and actual situation problems when using the transmission line pulse (TLP) testing methods, a modeling method based on the recurrent neural network
Zhiqiang JI   +3 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

A New Varying-Factor Finite-Time Recurrent Neural Network to Solve the Time-Varying Sylvester Equation Online

open access: yesMathematics
This paper presents a varying-parameter finite-time recurrent neural network, called a varying-factor finite-time recurrent neural network (VFFTRNN), which is able to solve the solution of the time-varying Sylvester equation online.
Haoming Tan   +6 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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