Results 51 to 60 of about 92,534 (217)

Signal demodulator based on in‐phase and quadrature interference‐robust feature

Electronics Letters, 2023
This letter examines the issue of mitigating strong co‐channel interference in communication systems is addressed. Unlike conventional model‐based methods, a novel data‐driven scheme is proposed.
Wen Deng, Xin Cai, Xiang Wang, Zhitao Huang   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

EMP response modeling of TVS based on the recurrent neural network

Journal of Hebei University of Science and Technology, 2015
Due to the larger workload in the implementation process and the poor consistence between the test results and actual situation problems when using the transmission line pulse (TLP) testing methods, a modeling method based on the recurrent neural network
Zhiqiang JI, Ming WEI, Qimeng WU, Yicheng YU   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A New Varying-Factor Finite-Time Recurrent Neural Network to Solve the Time-Varying Sylvester Equation Online

Mathematics
This paper presents a varying-parameter finite-time recurrent neural network, called a varying-factor finite-time recurrent neural network (VFFTRNN), which is able to solve the solution of the time-varying Sylvester equation online.
Haoming Tan, Junyun Wu, Hongjie Guan, Zhijun Zhang, Ling Tao, Qingmin Zhao, Chunquan Li   +6 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Exploring Efficient Neural Architectures for Linguistic–Acoustic Mapping in Text-To-Speech

Applied Sciences, 2019
Conversion from text to speech relies on the accurate mapping from linguistic to acoustic symbol sequences, for which current practice employs recurrent statistical models such as recurrent neural networks. Despite the good performance of such models (in
Santiago Pascual, Joan Serrà, Antonio Bonafonte   +2 more
doaj   +1 more source