Results 121 to 130 of about 3,541,809 (284)

Recurrent Pregnancy Loss: A Tragic Reproductive Failure

, 1970
Three or more consecutive pregnancy losses are considered as recurrent pregnancy loss (RPL). About 1% of all pregnant women face this distressing problem and o.5% to 5% of spontaneous abortions are recurrent.
Mst Rashida Begum, Mst Sahina Begum, Hosne Ara Baby, Maruf Siddiqui, Suha Jesmin, Mariya Ehsan   +5 more
core   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Predicting risk of the subsequent early pregnancy loss in women with recurrent pregnancy loss based on preconception data

BMC Women's Health
Background For women who have experienced recurrent pregnancy loss (RPL), it is crucial not only to treat them but also to evaluate the risk of recurrence. The study aimed to develop a risk predictive model to predict the subsequent early pregnancy loss (
Xin Yang, Ruifang Wang, Wei Zhang, Yanting Yang, Fang Wang   +4 more
doaj   +1 more source

Outpatient hysteroscopy in recurrent pregnancy loss

, 2018
Recurrent pregnancy loss is defined as the loss of three or more consecutive pregnancies. Common causes of recurrent pregnancy loss are endometritis, genetic abnormalities, congenital or acquired uterine malformation, endocrine dysfunction ...
Marinelli E., Resta L., Casavola V. C., Malvasi A., Cicinelli E., Trojano G., Tinelli A.   +6 more
core   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Timely care for extrauterine pregnancies during the COVID-19 pandemic is needed

The Lancet Regional Health. Europe, 2021
Nina la Cour Freiesleben, Henriette Svarre Nielsen   +1 more
doaj   +1 more source

Women’s experience of recurrent early pregnancy loss

, 1994
There is a paucity of research which explores women's experience with recurrent early pregnancy loss. This grounded theory study explored, described, and explained the basic social psychological process of recurrent early pregnancy loss.
Hogan, Catherine Ann
core   +1 more source

'Head-hunting' (or grief management) on Teesside: Pregnancy loss and the use of counselling as a ritual in the resolution of consequential grief [PDF]

, 2001
This anthropological thesis is based on an evaluation carried out at South Cleveland Hospital on Teesside, where midwives offer counselling to bereaved parents following pregnancy loss.
Brydon, Christine
core  

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source