Results 211 to 220 of about 64,247 (285)

Timing of diagnostic workups in Chinese population with recurrent pregnancy loss: a cross-sectional study [PDF]

Liyang Zhang, Yushu Du, Jingshuang Zhou, Chuanyang Liu, Jiapo Li, Chong Qiao   +5 more
openalex   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

Regulatory Mechanism and Drug Therapy of NLRP3 Inflammasome in Recurrent Pregnancy Loss: Research Status and Prospect. [PDF]

J Inflamm Res
Cui Y, Yang Y, Li Y, Zhang Y, Niu D, Feng X.   +5 more
europepmc   +1 more source

P-457 Increased prevalence of specific KIR phenotypes in a population of unexplained infertility with implantation failure and recurrent pregnancy loss: A retrospective study [PDF]

A Zavala-Garcia, H I Izquierdo-Urdinola, L Serrano-Palomo, J.A. Horcajadas, S Padure   +4 more
openalex   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Association Study of Hyaluronan-Binding Protein 2 (<i>HABP2</i>) Gene Polymorphisms in Idiopathic Recurrent Pregnancy Loss (RPL) in Korean Women. [PDF]

Int J Mol Sci
Lee JY, Kim YR, Ko EJ, Park HW, Lee JH, Hong SH, Shin JE, Ahn EH, Kim JH, Kim NK.   +9 more
europepmc   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Novel proteomics biomarkers of recurrent pregnancy loss reflect the dysregulation of immune interactions at the maternal-fetal interface. [PDF]

Front Immunol
Tóth E, Posta M, Györffy D, Oravecz O, Farkas E, Balogh A, Escher C, Bober M, Szilágyi A, Hupuczi P, Veress L, Török O, Nagy S, Rinner O, Erez O, Papp Z, Ács N, Than NG.   +17 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

LAG-3 palmitoylation-inducing dysfunction of decidual CD4⁺T cells is associated with recurrent pregnancy loss. [PDF]

Mol Med
Cui L, Sun F, Meng X, Luo Y, Qian J, Wang S.   +5 more
europepmc   +1 more source