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Recurrent Pregnancy Loss

open access: yesNature Reviews Disease Primers, 2020
Recurrent pregnancy loss is a distressing pregnancy disorder experienced by ~2.5% of women trying to conceive. Recurrent pregnancy loss is defined as the failure of two or more clinically recognized pregnancies before 20-24 weeks of gestation and includes embryonic and fetal losses. The diagnosis of an early pregnancy loss is relatively straightforward,
Eva Dimitriadis, William H Kutteh
exaly   +7 more sources
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Recurrent pregnancy loss

Current Opinion in Obstetrics and Gynecology, 1995
This review of recurrent pregnancy loss examines our current understanding of the major etiologies of this unfortunate condition including genetic and endocrine abnormalities, anatomic variations, autoimmune conditions, alloimmune problems, systemic disease, and infection. Diagnostic protocols and treatment strategies are briefly presented. With a high
C L, Cook, D D, Pridham
openaire   +2 more sources

Autoimmunity and Recurrent Pregnancy Losses

Clinical Reviews in Allergy & Immunology, 2009
The relationship between autoimmunity and reproduction has long been recognized. This relationship is bidirectional and includes many diverse issues, but in this review article, we focus on which autoimmune disturbances are the basic cause of recurrent pregnancy losses in patients with autoimmune diseases.
Ricard, Cervera, Juan, Balasch
openaire   +2 more sources

Cytogenetics of recurrent pregnancy loss

Russian Journal of Genetics, 2014
The contribution of chromosomal abnormalities to recurrent pregnancy loss (RLP) is reviewed in the paper. Data from conventional cytogenetic analysis of the karyotype of parents and spontaneous abortions, as well as the results of molecular cytogenetic investigations and preimplantation genetic diagnostics, are discussed.
T V, Nikitina, I N, Lebedev
openaire   +2 more sources

Cytokines in recurrent pregnancy loss

Clinica Chimica Acta, 2011
Recurrent pregnancy loss (RPL) is defined as the occurrence of three or more consecutive miscarriages prior to 20 weeks gestation. Exaggerated maternal immune response to fetal antigens has been proposed to be one of the mechanisms underlying recurrent pregnancy loss.A comprehensive literature search was conducted from the websites of the National ...
Vandana, Saini   +3 more
openaire   +2 more sources

Endocrinology of Recurrent Pregnancy Loss

Seminars in Reproductive Medicine, 2006
Following implantation, the maintenance of the pregnancy is dependent on a multitude of endocrinological events that will eventually aid in the successful growth and development of the fetus. Although the great majority of pregnant women have no pre-existing endocrine abnormalities, a small number of women can have certain endocrine alterations that ...
Francisco, Arredondo, Luis S, Noble
openaire   +2 more sources

Recurrent Pregnancy Loss

Clinical Obstetrics and Gynecology, 1986
Normal human reproduction is an inefficient process with only 22.8% of conceptive matings resulting in live birth (Fig. 1) (1,2). Miscarriages are the most common complication of pregnancy, affecting 15% of women (3). Loss of pregnancy is a physically and emotionally challenging ordeal.
openaire   +2 more sources

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