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Machine Learning Identified Mitophagy- and Hypoxia-Related Genes MTRNR2L8 and SUMO1P3 as Potential Biomarkers Associated with Unexplained Recurrent Pregnancy Loss. [PDF]
Fang Z, Zhang Y, Xu L, Wang X.
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Metabolic Reprogramming at the Maternal-Fetal Interface: Insights from Decidual Stromal Cells and Trophoblasts in Healthy Pregnancy Versus Recurrent Pregnancy Loss. [PDF]
Liu Z +7 more
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Genetic Polymorphisms of Vitamin D Receptor and Immune-Metabolic Mechanisms in Recurrent Pregnancy Loss: Narrative Review. [PDF]
Aimagambetova G +3 more
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Recurrent pregnancy loss is a distressing pregnancy disorder experienced by ~2.5% of women trying to conceive. Recurrent pregnancy loss is defined as the failure of two or more clinically recognized pregnancies before 20-24 weeks of gestation and includes embryonic and fetal losses. The diagnosis of an early pregnancy loss is relatively straightforward,
Eva Dimitriadis, William H Kutteh
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Current Opinion in Obstetrics and Gynecology, 1995
This review of recurrent pregnancy loss examines our current understanding of the major etiologies of this unfortunate condition including genetic and endocrine abnormalities, anatomic variations, autoimmune conditions, alloimmune problems, systemic disease, and infection. Diagnostic protocols and treatment strategies are briefly presented. With a high
C L, Cook, D D, Pridham
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This review of recurrent pregnancy loss examines our current understanding of the major etiologies of this unfortunate condition including genetic and endocrine abnormalities, anatomic variations, autoimmune conditions, alloimmune problems, systemic disease, and infection. Diagnostic protocols and treatment strategies are briefly presented. With a high
C L, Cook, D D, Pridham
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Autoimmunity and Recurrent Pregnancy Losses
Clinical Reviews in Allergy & Immunology, 2009The relationship between autoimmunity and reproduction has long been recognized. This relationship is bidirectional and includes many diverse issues, but in this review article, we focus on which autoimmune disturbances are the basic cause of recurrent pregnancy losses in patients with autoimmune diseases.
Ricard, Cervera, Juan, Balasch
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Cytogenetics of recurrent pregnancy loss
Russian Journal of Genetics, 2014The contribution of chromosomal abnormalities to recurrent pregnancy loss (RLP) is reviewed in the paper. Data from conventional cytogenetic analysis of the karyotype of parents and spontaneous abortions, as well as the results of molecular cytogenetic investigations and preimplantation genetic diagnostics, are discussed.
T V, Nikitina, I N, Lebedev
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Cytokines in recurrent pregnancy loss
Clinica Chimica Acta, 2011Recurrent pregnancy loss (RPL) is defined as the occurrence of three or more consecutive miscarriages prior to 20 weeks gestation. Exaggerated maternal immune response to fetal antigens has been proposed to be one of the mechanisms underlying recurrent pregnancy loss.A comprehensive literature search was conducted from the websites of the National ...
Vandana, Saini +3 more
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Endocrinology of Recurrent Pregnancy Loss
Seminars in Reproductive Medicine, 2006Following implantation, the maintenance of the pregnancy is dependent on a multitude of endocrinological events that will eventually aid in the successful growth and development of the fetus. Although the great majority of pregnant women have no pre-existing endocrine abnormalities, a small number of women can have certain endocrine alterations that ...
Francisco, Arredondo, Luis S, Noble
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Clinical Obstetrics and Gynecology, 1986
Normal human reproduction is an inefficient process with only 22.8% of conceptive matings resulting in live birth (Fig. 1) (1,2). Miscarriages are the most common complication of pregnancy, affecting 15% of women (3). Loss of pregnancy is a physically and emotionally challenging ordeal.
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Normal human reproduction is an inefficient process with only 22.8% of conceptive matings resulting in live birth (Fig. 1) (1,2). Miscarriages are the most common complication of pregnancy, affecting 15% of women (3). Loss of pregnancy is a physically and emotionally challenging ordeal.
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