Results 41 to 50 of about 255,363 (351)

Circulating levels of matrix proteases and their inhibitors in pregnant women with and without a history of recurrent pregnancy loss [PDF]

, 2010
Background: We have recently shown that serum relaxin-2 levels are attenuated in women with a history of recurrent pregnancy loss (RPL). We sought to determine whether a history of RPL is also associated with changes in serum matrix metalloproteases ...
Anumba, D.O.C., El Gelany, S., Elliott, S.L., Li, T.C.   +3 more
core   +3 more sources

Pregnancy loss and risk of multiple sclerosis and autoimmune neurological disorder: A nationwide cohort study.

PLoS ONE, 2022
BackgroundThe loss of one or more pregnancies before viability (i.e. pregnancy loss or miscarriage), has been linked to an increased risk of diseases later in life such as myocardial infarction and stroke. Recurrent pregnancy loss (i.e. three consecutive
Anders Pretzmann Mikkelsen, Pia Egerup, Astrid Marie Kolte, David Westergaard, Henriette Svarre Nielsen, Øjvind Lidegaard   +5 more
doaj   +1 more source

Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester [PDF]

, 2009
Objectives: Defective implantation is a mechanism for recurrent pregnancy loss (RPL). We sought to determine whether the serum expression of human relaxin-2 (RLX) is impaired in women with a history of RPL.
Bogic, Bogic, Carp, Craig, Dilly O.C. Anumba, Emmer, Gardosi, Goldsmith, Hollis, Jauniaux, Jivraj, Johnson, Johnson, Laird, MacLennan, Maynard, Mtiraoui, Nicolaides, Palomba, Parry, Petersen, Piccinni, Prakash, Saad El Gelany, Sakbun, Salim, Sarah L. Elliott, Seki, Tin C. Li, Unemori, Yki-Jarvinen   +30 more
core   +1 more source

The role of oxidative stress in patients with recurrent pregnancy loss: a review

Reproductive Health, 2021
Background Recurrent pregnancy loss (RPL) presents one of the main problems in the field of reproductive medicine, due to the unknown etiology in 50% of cases, as well as limited evidence-based diagnostic and therapeutic modalities.
Vjosa A. Zejnullahu, Valon A. Zejnullahu, Ernad Kosumi   +2 more
semanticscholar   +1 more source

DNA Methylation and Recurrent Pregnancy Loss: A Mysterious Compass?

Frontiers in Immunology, 2021
Recurrent pregnancy loss (RPL) is a common and severe pathological pregnancy, whose pathogenesis is not fully understood. With the development of epigenetics, the study of DNA methylation, provides a new perspective on the pathogenesis and therapy of RPL.
Qi Zhou, Yunhe Xiong, Bing Qu, A. Bao, Yan Zhang   +4 more
semanticscholar   +1 more source

Chronic Infection in Recurrent Pregnancy Loss

Fertility & Reproduction, 2023
In the present study, the effects of chronic endometritis (CE) on implantation and pregnancy outcomes, the effects of CE on endometrial function, and the effects of progesterone as a treatment for CE were examined.
Fuminori Kimura
doaj   +1 more source

Recurrent pregnancy loss

Van Tıp Dergisi, 2017
Recurrent loss of pregnancy (RLP), consecutive loss of three pregnancies before 20 week of pregnancy. Multifactorial causes play a role in etiology. However, in many cases a definite reason can not be established.
Şerif Aksin
doaj   +1 more source

Oxidative/nitrosative stress increased the risk of recurrent pregnancy loss–Taiwan Recurrent Pregnancy Loss and Environmental Study (TREPLES)

Redox Biology, 2023
Objective: Oxidative stress biomarkers (OSBs) may be strongly associated with disease progression and recurrent pregnancy loss (RPL). However, the research on associations of most OSBs (e.g., 8-nitroguanine [8-NO2Gua] and 4-hydroxy-2-nonenal-mercapturic ...
Yu-Jung Lin, Wei-Hsiang Chang, Pao-Lin Kuo, Hsin-Chang Chen, Wan-Ting Chang, Po-Chin Huang   +5 more
doaj   +1 more source

Clinical Relevance of Vaginal and Endometrial Microbiome Investigation in Women with Repeated Implantation Failure and Recurrent Pregnancy Loss

International Journal of Molecular Sciences
Recent studies have investigated if and how the vaginal and endometrial microbiome might affect endometrial receptivity and reproductive health. Although there is no consensus on the existence of a core uterine microbiome yet, evidence shows that the ...
Xushan Gao, Y. Louwers, J. Laven, S. Schoenmakers   +3 more
semanticscholar   +1 more source

ESHRE guideline: recurrent pregnancy loss

Human Reproduction Open, 2018
STUDY QUESTION What is the recommended management of women with recurrent pregnancy loss (RPL) based on the best available evidence in the literature? SUMMARY ANSWER The guideline development group formulated 77 recommendations answering 18 key questions
Ruth Bender Atik, O. Christiansen, J. Elson, A. Kolte, S. Lewis, S. Middeldorp, W. Nelen, B. Peramo, S. Quenby, N. Vermeulen, M. Goddijn   +10 more
semanticscholar   +1 more source