Results 61 to 70 of about 234,611 (389)

The Association Between Sperm DNA Fragmentation and Idiopathic Early Recurrent Pregnancy Loss [PDF]

, 2016
IntroductionVarious etiologies of recurrent pregnancy loss (RPL) have been extensively studied, but more than half of them still remain unknown. Male factor may play a role in incidence of idiopathic early recurrent pregnancy loss.
Halim, Binarwan, Putri Lubis, Hilma
core   +2 more sources

Association between Chlamydia trachomatis infection and recurrent pregnancy loss [PDF]

, 2022
Background: Chlamydia trachomatis infection is widely prevalent sexually transmitted infection. Chlamydia trachomatis is associated with pelvic inflammatory disease, salpingitis, infertility and various adverse pregnancy outcomes example- preterm labour,
., Shaheen, Saxena, Upma
core   +2 more sources

Association between polymorphism of has-miR-125 (rs12976445) and susceptibility to idiopathic recurrent pregnancy loss in Iranian women [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Many new studies related to peri-implantation period and maintenance of pregnancy suggest that microRNAs have fundamentally role in regulating critical pathways in early pregnancy loss and implantation failure. This study was performed with
Sara Nemati Vahedi, Babak Kheirkhah, Ali Akbar Malekirad   +2 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Defining Vaginal Community Dynamics: daily microbiome transitions, the role of menstruation, bacteriophages, and bacterial genes

Microbiome
Background The composition of the vaginal microbiota during the menstrual cycle is dynamic, with some women remaining eu- or dysbiotic and others transitioning between these states.
Luisa W. Hugerth, Maria Christine Krog, Kilian Vomstein, Juan Du, Zahra Bashir, Vilde Kaldhusdal, Emma Fransson, Lars Engstrand, Henriette Svarre Nielsen, Ina Schuppe-Koistinen   +9 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Endometrial Immune Dysfunction in Recurrent Pregnancy Loss

International Journal of Molecular Sciences, 2019
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is also a significant reproductive disorder affecting around 5% of couples ...
C. Ticconi, A. Pietropolli, N. Di Simone, E. Piccione, A. Fazleabas   +4 more
semanticscholar   +1 more source

Lack of Association between Recurrent Pregnancy Loss and Inherited Thrombophilia in a Group of Colombian Patients [PDF]

, 2012
Studies have shown an association between recurrent pregnancy loss and inherited thrombophilia in Caucasian populations, but there is insufficient knowledge concerning triethnic populations such as the Colombian.
Alvarez, Leonor, Bedoya, Gabriel, Cadavid, Ángela P., Cardona Maya, Wálter, Cardona, Henry, Castañeda, Serguei A., Gómez, Joaquín, Gómez, Jorge, Tobón, Luis, Torres, José   +9 more
core   +3 more sources

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source