Results 71 to 80 of about 165,153 (331)
Advanced Science, EarlyView.This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai +9 more
wiley +1 more source
Obstetrics and Gynecology International, 2015 Objective. Women with infertility and recurrent miscarriages may have an overlapping etiology. The aim of this study was to compare the pregnancy loss in pregnancies after IVF treatment with spontaneous pregnancies in women with recurrent miscarriages ...
Vidya A. Tamhankar +3 more
doaj +1 more source
Advanced Science, EarlyView.Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang +5 more
wiley +1 more source
Etiologic analysis of recurrent pregnancy losses
Van Tıp Dergisi, 2017 INTRODUCTION: Two or more consecutive loss of pregnancy prior to 20 weeks is called recurrent pregnancy loss. We reviewed the records retrospectively and analyzed the etiology of recurrent pregnancy losses in our region.
Şerif Aksin, Cengiz Andan
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Automatically Identifying Comparator Groups on Twitter for Digital Epidemiology of Pregnancy Outcomes [PDF]
arXiv, 2019 Despite the prevalence of adverse pregnancy outcomes such as miscarriage, stillbirth, birth defects, and preterm birth, their causes are largely unknown. We seek to advance the use of social media for observational studies of pregnancy outcomes by developing a natural language processing pipeline for automatically identifying users from which to select
arxiv
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
T cells in normal pregnancy and recurrent pregnancy loss [PDF]
Reproductive BioMedicine Online, 2006 This review focuses on the possible role of T cells in successful pregnancy and in unexplained recurrent abortion. The functions exhibited by Th1 and Th2 cells have suggested, perhaps in a simplistic way, that Th1-type cytokines, which promote allograft rejection, may compromise pregnancy, whereas the Th2-type cytokines, by inhibiting Th1 responses ...
openaire +5 more sources
Advanced Science, EarlyView.A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao +15 more
wiley +1 more source
Advanced Science, EarlyView.Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo +11 more
wiley +1 more source
Molecular Mechanisms of Recurrent Pregnancy Loss
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020 Introduction: Pregnancy and health is the process in which the egg is fertilized and being able to survive. When pregnancy occurs under some conditions and the fetus is being at risk, it will lead to abortion that occurs involuntarily and spontaneously ...
Bahareh Mazrouei +3 more
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