Results 111 to 120 of about 587,390 (283)

Physiologically Based Pharmacokinetic Modeling to Assess Transporter‐Mediated Drug–Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray

Clinical Pharmacology &Therapeutics, EarlyView.
Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke, Ernesto Callegari, Manthena V.S. Varma, Mayur K Ladumor, Chieko Muto, Richard J. Bertz, Hannah M. Jones, Vaishali Sahasrabudhe, Jing Liu   +8 more
wiley   +1 more source

Catamenial cyclic vomiting syndrome responding to oestrogen therapy: an adolescent case report

The Pan African Medical Journal, 2019
Cyclic vomiting syndrome (CVS) is defined by episodes of vomiting lasting from a few hours to several days, alternating with periods of no symptoms. Various symptoms can be associated with vomiting such as nausea, migraine or abdominal pain.
Moulay El Mehdi El Hassani, Benali Saad, Moukit Mounir, Jaouad Kouach, Driss Moussaoui Rahali   +4 more
doaj   +1 more source

An unusual case of hyperthyroidism with recurrent vomiting and hypercalcemia as the main manifestations. [PDF]

J Int Med Res, 2022
Wei XD, Tan JP, Chen XM.
europepmc   +1 more source

RECURRENT VOMITING IN CHILDREN [PDF]

BMJ, 1905
H B, Shaw, R H, Tribe
openaire   +2 more sources

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

Clinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit, Maaike van Dartel, Laura Rodwell, Hanneke van der Woude, Cornelis Boersma, Peter G. M. Mol, Doranne Hilarius   +6 more
wiley   +1 more source

Annular Pancreas Presenting with Intermittent Duodenal Obstruction in Early Childhood: A Diagnostic Masquerade

Reports
Background and Clinical Significance: Annular pancreas is a rare congenital anomaly in which pancreatic tissue partially or completely encircles the duodenum, potentially causing duodenal obstruction.
Maria Rogalidou, Georgios Papagiannis, Paraskevi Galina, Evangelia Lykopoulou, Konstantina Dimakou, Alexandra Papadopoulou   +5 more
doaj   +1 more source

A Little Support Goes a Long Way: A Mixed‐Methods Pilot Study of Supported Digital CBTe for Recurrent Binge Eating

International Journal of Eating Disorders, EarlyView.
ABSTRACT Background Eating disorders characterized by recurrent binge eating are prevalent, impairing, and undertreated. Digital programme‐led interventions may increase access to recommended treatments, but completion rates are variable. Adding brief human support to digital programmes may improve completion and outcomes.
Rebecca Murphy, Emma L. Osborne, Charandeep K. Khera   +2 more
wiley   +1 more source

Feasibility, Acceptability and Outcomes of Group CBT‐T: A Naturalistic Mixed‐Methods Comparison With Individual CBT‐T

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study aimed to evaluate the feasibility of implementing 10‐session group cognitive behavioural therapy (CBT‐Tg) in routine outpatient eating disorder care and to descriptively examine outcomes of CBT‐Tg and individual CBT‐T (CBT‐Ti). Method Using a naturalistic, non‐randomised, mixed‐methods design, this implementation study was
Laura Dixon, Anastasia Harris, Victoria Taylor, Lily Spoozak, Sara Bartel, Susan Gamberg, Nami Trappenberg, Colby Price, Navjot Sandila, Elena Koning, Sarrah I. Ali, Erin Piercy, Glenn Waller, Aaron Keshen   +13 more
wiley   +1 more source

Empirically Defining “Recurrent” Inappropriate Compensatory Behaviors: Differentiating Binge Eating Disorder From Bulimia Nervosa‐Spectrum Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective For multiple disorders, DSM‐5‐TR criteria include “recurrent” engagement in behaviors—for example, in the criteria for binge‐eating disorder (BED), “binge eating is not associated with the recurrent use of inappropriate compensatory behavior.”—without operationalizing how frequently a behavior needs to occur to be considered ...
Sophie R. Abber, Dan V. Blalock, Renee D. Rienecke, Philip S. Mehler, Alan Duffy, Jamie Manwaring, Maryrose Bauschka, Kimberly Anderson, Harry A. Brandt, Craig Johnson, Timothy Brewerton, Thomas E. Joiner, Lauren N. Forrest   +12 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source