Results 171 to 180 of about 587,390 (283)

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Transthyretin-related hereditary amyloidosis with recurrent vomiting and renal insufficiency as the initial presentation: A case report. [PDF]

Medicine (Baltimore), 2017
Xu J, Yang M, Pan X, Yu X, Xie J, Ren H, Li X, Chen N.   +7 more
europepmc   +1 more source

CHAPLE‐Like Enteropathy and Renal Microangiopathy in an Adult Patient With CD46 Deficiency

Journal of Clinical Laboratory Analysis, EarlyView.
We report an adult patient with a homozygous CD46 variant presenting with lifelong protein‐losing enteropathy, intestinal lymphangiectasia, and CVID‐like hypogammaglobulinemia mimicking CHAPLE syndrome. Concurrent renal biopsy revealed PLA2R‐negative membranous nephropathy with chronic thrombotic microangiopathy, establishing multi‐organ complement ...
Bircan Erden, Pelin Korkmaz, Halil Yazici, Ahmet Burak Dirim, Fatih Beşışık, Nevzat Kahveci, Zeynep Kilinc, Derya Unal, Osman Ozan Yegit, Tuğba Kalaycı, Özge Hürdoğan, Yasemin Özlük, Melek Büyük, Asli Gelincik, Semra Demir   +14 more
wiley   +1 more source

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

Journal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia, Binquan Chu, Fengjun Chen, Xiangyu Zhu, Chen Hang, Xiaoling Yu, Jinpiao Lin   +6 more
wiley   +1 more source

Adult intestinal malrotation presenting as recurrent vomiting: a case report. [PDF]

Indian J Surg, 2015
Jadhav RR, Pai VD.
europepmc   +1 more source

Incidental Detection of Portal Venous Gas During POCUS in a Neonate With Necrotizing Enterocolitis and Intestinal Perforation: A Case Report

Journal of Clinical Ultrasound, EarlyView.
Point‐of‐care ultrasound performed at the bedside identified hepatic portal venous gas in a critically ill neonate, prompting urgent evaluation and revealing intestinal perforation due to necrotizing enterocolitis. This case highlights the potential of POCUS to accelerate diagnosis when clinical signs are subtle or nonspecific.
Tiago Henrique de Souza, Elisa Caixeta Fallieri Nascimento, Fernando de Lima Carioca, Nayara Hillebrand Franzon, Humberto Magalhães Silva   +4 more
wiley   +1 more source

The prevalence of eating difficulties in children and young people in England: A large, cross‐sectional school survey

JCPP Advances, EarlyView.
Abstract Background Accurate population prevalence estimates of eating difficulties in children and young people provide essential information for the design and implementation of prevention efforts. We aimed to (I) explore the proportion of students reporting eating difficulties in a large English secondary school sample, (II) analyse factors ...
Clara Faria, The OxWell Study Team, Mina Fazel, Emma Soneson, Tamsin J. Ford, Simon White   +5 more
wiley   +1 more source

Validation of Virtual Reality Simulations for Anatomical Landmarks in Panoramic Radiographs

Journal of Dental Education, EarlyView.
ABSTRACT Objective This study assessed the validity of panoramic anatomical virtual reality (VR) software among senior dental students. Materials and Methods A total of 79 fourth‐year dental students were randomly divided into two groups in this crossover study. Students’ knowledge of panoramic anatomical landmarks was tested.
Daniah M. Alhazmi, Sarah Alnamlah, Noura Alsufyani, Asma'a Faden, Fatima M. Jadu   +4 more
wiley   +1 more source

AI‐Powered Virtual Patients in Health Professions Education: Learner Engagement and Knowledge Application

Journal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives Immersive educational technologies, including applications of artificial intelligence in education (AIED), are increasingly used to develop clinical skills in health professions education. This study evaluated the feasibility and perceived value of integrating an artificial intelligence (AI)‐enabled virtual patient platform ...
Jeffrey J. Borckardt, Debra E. Henninger‐Borckardt, Joe Vuthiganon, Dusti Annan‐Coultas, Lisa Langdale, Kimberly Kascak, Lindsey Hamil   +6 more
wiley   +1 more source