Results 51 to 60 of about 1,098,786 (335)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
The Largest Environmental Movement: Recycling and Consumption Work in Sweden [PDF]
By sorting their waste for recycling, Swedes are told that they are part of 'Sweden's largest environmental movement' (Avfall Sverige, 2008). Recycling in Sweden is understood as an environmental action by all parties within society (including consumers,
Wheeler, Kathryn
core
Recyclability of Recycled Concrete Products in Cements
This research addresses the recycling possibilities of a concrete product that contains coarse concrete aggregate as recycled material. The use of this finely milled product is proposed as an active addition to cement that already includes by-products in their composition.
Santiag Rosado+3 more
openaire +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
We consider a deterministic realization of Parrondo games and use periodic orbit theory to analyze their asymptotic behavior.Comment: 12 pages, 9 ...
Artuso R+9 more
core +1 more source
Quantum Noise in Differential-type Gravitational-wave Interferometer and Signal Recycling [PDF]
There exists the standard quantum limit (SQL), derived from Heisenberg's uncertainty relation, in the sensitivity of laser interferometer gravitational-wave detectors.
Kawamura, Seiji+2 more
core +2 more sources
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Modeling and scenario prediction of a natural gas demand system based on a system dynamics method
Based on the study of the relationship between structure and feedback of China’s natural gas demand system, this paper establishes a system dynamics model. In order to simulate the total demand and consumption structure of natural gas in China, we set up
Xian-Zhong Mu, Guo-Hao Li, Guang-Wen Hu
doaj +1 more source
Transfer Functions for Fields in a 3-mirror Nested Cavity [PDF]
Transfer functions for the fields in a 3-mirror nested cavity are obtained. Explicit formulas for their poles and zeros are found.
Rakhmanov, Malik
core +1 more source
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source