Results 111 to 120 of about 262,804 (235)

Leadership Lessons From a Quality Improvement Project to Decrease the Avoidable Days in the Hospital Related to Decision-Making Capacity. [PDF]

Cureus
Fatima H, Atif S, Ayala B, Mian ZR, Zareen S, Azhar E, Waheed A.   +6 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Applying the advocacy coalition framework to wildlife management: Explaining policy change for damage mitigation in Japan. [PDF]

PLoS One
Koga T.
europepmc   +1 more source

Formal Models of Elections and Political Bargaining [PDF]

The key theoretical idea in this paper is that activist groups contribute resources to their favored parties in response to policy concessions from the parties.
Norman Schofield, Ugur Ozdemir
core   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

A Comprehensive School-Based Mental Health Model: A Decade in the Making. [PDF]

Behav Sci (Basel)
Reinke WM, Herman KC, Thompson A, Owens S.   +3 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The Platform Readiness Dashboard: A Tool for Evaluating Vaccine Platform Suitability for a Rapid Response to Epidemic and Pandemic Threats. [PDF]

Vaccines (Basel)
Sabet-Azad R, Hoath C, Bézay N, Särnefält A.   +3 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Explainable artificial intelligence for molecular design in pharmaceutical research. [PDF]

Chem Sci
Lamens A, Bajorath J.
europepmc   +1 more source