Results 41 to 50 of about 719,654 (263)
A Density Functional Theory Study of Raman Modes of Hydrogenated Cadmium Sulphide Nanoparticles
Raman scattering investigations based on density functional theory (DFT) calculations were performed to explore the vibrational modes of wurtzite structured CdS nanoparticles (NPs).
Abdul Majid +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
mBeRFP, an improved large stokes shift red fluorescent protein.
Herein, we describe the generation of a monomeric large Stokes shift (LSS) red fluorescent protein, mBeRFP, with excitation and emission peaks at 446 and 615 nm, respectively. Compared with two previously reported LSS-RFPs (mKeima and LSS-mKate2), mBeRFP
Jie Yang +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Starvation Stress Causes Body Color Change and Pigment Degradation in Acyrthosiphon pisum
The pea aphid, Acyrthosiphon pisum (Harris), shows body color shifting from red to pale under starvation in laboratory conditions. These body color changes reflect aphid’s adaptation to environmental stress. To understand the color-shifting patterns, the
Xing-Xing Wang +6 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
THE recent development of the technique of resonant scattering of γ-rays, using the Mossbauer effect, appears to raise the possibility of a terrestrial test of one theory of the red shift observed by Hubble in the light coming from distant galaxies.
openaire +1 more source
Gravitational Red-shift in Nuclear Resonance [PDF]
The several theories of relativity predict the frequency of electromagnetic spectral lines to be proportional to the gravitational potential. Experiments are proposed to observe the timekeeping of a "clcck" based on an atomic or molecular transition, when held aloft in a rocket-launched satellite, relative to a similar one kept on the ground.
R. V. Pound, G. A. Rebka
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