Results 81 to 90 of about 4,409,042 (310)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Shift work: An occupational health and safety hazard

, 2003
Shift work is a major feature of modern work practices. It involves individuals working at times considered unconventional for most workers, such as at night.
Buxton, Sandra
core  

Anion-Responsive Colorimetric and Fluorometric Red-Shift in Triarylborane Derivatives: Dual Role of Phenazaborine as Lewis Acid and Electron Donor

Photophysical modulation of triarylboranes (TABs) through Lewis acid-base interactions is a fundamental approach in sensing anions. Yet, design principles for anion-responsive TABs displaying significant red-shift in absorption and photoluminescence (PL)
Riku, Nakagawa, Satoshi , Minakata, Leonardo Evaristo, de Sousa, Norimitsu, Tohnai, Nae, Aota, Piotr, de Silva, Youhei, Takeda   +6 more
core   +1 more source

Reduced-Complexity QAM-Aided Space-Time Shift Keying

, 2011
A novel reduced-complexity near-optimal detection algorithm is proposed for enhancing the recent coherently-detected Space-Time Shift Keying (STSK) scheme employing arbitrary constellations, such as L-point Phase-Shift Keying (PSK) and Quadrature ...
S. Sugiura, Sugiura, Shinya, Chao Xu, L. Hanzo, Xu, Chao, Hanzo, Lajos   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Actively tunable terahertz chain-link metamaterial with bidirectional polarization-dependent characteristic

Scientific Reports, 2019
A tunable terahertz (THz) chain-link metamaterial (CLM) is presented, which is composed of a tailored Au layer fabricated on Si substrate. CLM exhibits bidirectional polarization-dependent characteristic by applying a direct-current (dc) bias voltage on ...
Pengyu Liu, Zihao Liang, Zhicheng Lin, Zefeng Xu, Ruijia Xu, Dongyuan Yao, Yu-Sheng Lin   +6 more
doaj   +1 more source

red shift

, 2014
Citation: 'red shift' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05211 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Mean reaction time (Standard deviation) for the Vertical-shift-object and Non-vertical-shift-object in the Spatial recall task and the Identity Task across four experiments.

, 2016
Mean reaction time (Standard deviation) for the Vertical-shift-object and Non-vertical-shift-object in the Spatial recall task and the Identity Task across four experiments.
David Uttal (3190695), Lei Yuan (713591), Steven Franconeri (3190698)   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Tunable perfect meta-absorber with high sensitivity for refractive index sensing application

Sensing and Bio-Sensing Research
An infrared (IR) tunable perfect meta-absorber (TPM) is presented, which is configured of metal-insulator-metal (MIM) structure. The unit cell of the TPM device is composed of two opposite T-shaped and two rod-shaped Au resonators on the reflective ...
Kunye Li, Yu-Sheng Lin
doaj   +1 more source