Results 41 to 50 of about 11,378,899 (295)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
La web 2.0: Herramienta de marketing y posicionamiento de los cibermedios iberoamericanos
Cuadernos.info, 2010 El presente artículo analiza las diferentes aplicaciones de la web social en los cibermedios de América Latina, España y Portugal. El estudio, derivado de una investigación aplicada a 70 medios de comunicación online, y basado en consultas a ...
SANTIAGO TEJEDOR
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Welfare finance reform: District states could face funding challenges [PDF]
Welfare finance reform could have a substantial fiscal impact on the budgets of some states in the Tenth district, although the ability to cope with reform will vary from state to state.
Deron Ferguson
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
IDP, 2005 En aquest primer número de la revista el monogràfic se centra en l'anàlisi de la convergència que, sota el paraigua de l'OMPI i l'OMC, s'està produint entre els dos grans sistemes de protecció dels drets d'autor (el sistema de copyright anglosaxó i el ...
Pere Fabra
doaj +1 more source
An emerging computer sector in the Tenth District [PDF]
Computer industries have been an important facet of the nation's current economic expansion. During the 1990s, the computer sector has added almost three-quarters of a million jobs across the country, creating high-paying new positions and spawning new ...
Jason Henderson
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
EIN NEUES LEBEN: ROT-SCHWARZ ROT
Anadolu Üniversitesi Eğitim Fakültesi dergisi, 2018 Es waren gerade mal zwei Jahre, dass ich in diese Stadt kam. Als ich an dem Busbahnhof in einer Zeit ankam, in der die Sterne trödelten, hatte ich bereits gespürt, dass auch mein Schicksal hier genauso wie die dunkle Nacht sein würde, dunkel wie Teer ...
Gülcan Çakır
doaj