Results 81 to 90 of about 3,693,588 (251)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

American National Red Cross Hurricane Disaster Action

open access: yes, 1971
28 pages; available for download at the link below.The American National Red Cross under its congressional charter has the responsibility "to continue and carry on a system of national and international relief in time of peace and apply the same in ...
American National Red Cross
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Semantic and structural analysis of lexis denoting color in Russian language

open access: yesJournal of Education, Health and Sport, 2017
The article determines an analysis of the lexis, used to express color in Russian. To achieve this aim, the theoretical aspect as well as the collected files of the selected linguistic units serving as the research material were presented.
Marta Nowaczyk
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Libros y ruralidad: geografías andinas de la Red de Bibliotecas Rurales de Cajamarca, Perú

open access: yesRevista Interamericana de Bibliotecología, 2020
La Red de Bibliotecas Rurales de Cajamarca es una organización sin ánimo de lucro conformada por las familias comuneras del territorio de Cajamarca, en la sierra norte del Perú, que con los libros en el campo han logrado afianzar y extender la tradición ...
Nathalia Quintero Castro   +1 more
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Group portrait in Red Cloud, Nebraska

open access: yes, 1885
A photograph of a group of Red Cloud, Nebraska, citizens. They are: back row left: Dave Kaley, Bess Seymour, P D Yeiser, Tom Ferris, Bert Cromwell, Anna Kaley, Ryland Yeiser; middle row left: Ed Hasford, Laird Wallace, Clara Becker; front row left ...
Bradbrook, Red Cloud, NE
core  

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