Results 61 to 70 of about 4,026,934 (274)

Layer‐Specific Dermal and Subcutaneous Delivery via Modular LNP–Hydrogel‐Integrated Threaded Microneedles

open access: yesAdvanced Science, EarlyView.
Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie   +14 more
wiley   +1 more source

Low incidence of HIV infection in an anonymous HIV counselling and testing clinic cohort in Bangkok, Thailand despite high HIV prevalence and self-report of high-risk behaviour

open access: yesJournal of Virus Eradication, 2015
Background: HIV counselling and testing (HCT) clinics have the potential to be entry points for recruiting populations at high risk for HIV infection for HIV prevention and treatment studies.
Nittaya Phanuphak   +12 more
doaj   +3 more sources

Opór pamięci i fotografie kultury historycznej. Nekropolie Armii Czerwonej

open access: yesTeksty Drugie, 2020
Polish laws prohibiting the promotion of communism (Dz. U. Journal of Laws 2016 no. 744, as well as 2017 nos 1389 and 2495) reawakened controversies on Red Army monuments and memorials on Polish territory and their belonging to the nation’s cultural ...
Patrycja Cembrzyńska
doaj  

Cultural and Domestic Arrangement of Migrant Kolkhozes and the Daily Life of Settlers in the North Caucasus Region in the Period of Collectivization

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2016
In the present article based on rare archival materials for the first time used in scientific circulation the author examines the issues of cultural and domestic arrangement of migrant kolkhozes (collective farms) in the North Caucasus region in the ...
Istyagin Vadim R.
doaj   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao   +10 more
wiley   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li   +11 more
wiley   +1 more source

Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu   +5 more
wiley   +1 more source

Forced Mobilization into the Red Army (1944–1945)

open access: yesGenocidas ir Rezistencija, 2013
Forced mobilisation into the occupying Soviet army in August 1944–May 1945 became an integral part of the terror against the population of Lithuania. The Soviet Union, which in the second half of 1944 launched a call-up of Lithuanian men to the Red Army,
Vytautas Tininis
doaj   +1 more source

Comparison of rat hypertrophic scar models: Caudal tension model with superior pathological consistency

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study compared hypertrophic scar (HS) formation in SD rats at ear, back, and tail sites with or without mechanical tension. The ear model healed spontaneously by day 30. Dorsal full‐thickness excision (1 × 8 cm) produced moderate HS. In contrast, the tail tension model showed the greatest scar thickness, fibroblast density, collagen deposition ...
Lingyi Zhan   +10 more
wiley   +1 more source

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