Results 101 to 110 of about 1,861,746 (338)

Is There any Relationship Between the Repeated Complications of Sickle Cell Disease and the Potential Development of Acute Leukemia?

Oncology and Therapy
Sickle cell disease (SCD) is a severe monogenic hereditary hemoglobinopathy that is characterized by repeated clinical and biological manifestations able to generate stress erythopoiesis.
Giovanna Cannas, Mohamed Elhamri, Xavier Thomas   +2 more
doaj   +1 more source

Validation of the Medonic CA620/530 Vet 20-ml microcapillary sampler system for hematology testing of feline blood [PDF]

, 2009
The aim of the current study was to compare feline hematologic variables in blood collected in microcapillary tubes (20 ml) and conventional blood tubes with the Medonic CA620/530 Vet in-house hematologic analyzer.
Bourges-Abella, Nathalie, Braun, Jean-Pierre, Geffré, Anne, Reynolds, Brice, Trumel, Catherine   +4 more
core  

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Role of Piezo1 in Terminal Density Reversal of Red Blood Cells

Cells
Density reversal of senescent red blood cells has been known for a long time, yet the identity of the candidate ion transporter(s) causing the senescent cells to swell is still elusive.
Kuntal Dey, Ankie M. van Cromvoirt, Inga Hegemann, Jeroen S. Goede, Anna Bogdanova   +4 more
doaj   +1 more source

Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22

Frontiers in Immunology, 2018
Resolution-phase macrophage population orchestrates active dampening of the inflammation by secreting anti-inflammatory and proresolving products including interleukin (IL)-10 and lipid mediators (LMs).
Kati Hyvärinen, Minna Holopainen, Vita Skirdenko, Hanna Ruhanen, Hanna Ruhanen, Petri Lehenkari, Petri Lehenkari, Petri Lehenkari, Matti Korhonen, Reijo Käkelä, Saara Laitinen, Erja Kerkelä   +11 more
doaj   +1 more source

A simplified model for red cell dynamics in small blood vessels

, 1998
A simple mechanism for the confinement of red cells in the middle of narrow blood vessels is proposed. In the presence of a quadratic shear, red cells deform in such a way to loose fore-aft symmetry and to achieve a fixed orientation with respect to the ...
Olla, Piero
core   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Beyond adenosine triphosphate: unveiling the pleiotropic effects of pyruvate kinase activation in sickle cell anemia

Haematologica
Not available.
Andreas Glenthøj
doaj   +1 more source

Is Increased Intracellular Calcium in Red Blood Cells a Common Component in the Molecular Mechanism Causing Anemia?

Frontiers in Physiology, 2017
For many hereditary disorders, although the underlying genetic mutation may be known, the molecular mechanism leading to hemolytic anemia is still unclear and needs further investigation.
Laura Hertz, Rick Huisjes, Esther Llaudet-Planas, Polina Petkova-Kirova, Asya Makhro, Jens G. Danielczok, Stephane Egee, Stephane Egee, Stephane Egee, Maria del Mar Mañú-Pereira, Richard van Wijk, Joan-Lluis Vives Corrons, Anna Bogdanova, Lars Kaestner, Lars Kaestner   +14 more
doaj   +1 more source

Artificial neural networks for 3D cell shape recognition from confocal images

, 2020
We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood disease ...
Bianchi, P., Chachanidze, R., Fermo, E., Hinkelmann, K., Kaestner, L., Leonetti, M., Quint, S., Simionato, G., van Wijk, R., Wagner, C.   +9 more
core   +2 more sources