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Cryopreservation of Red Blood Cells
2018Glycerol and trehalose are widely used protective agents in the cryopreservation of red blood cells (RBCs). This chapter presents a protocol for use of these agents as cryoprotectants of RBCs, with post-thaw assessment of cell survival and cellular oxidative-reductive status. The main aim is to provide a framework for further studies aimed at improving
Noha A S Al-Otaibi +3 more
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1982
The red blood cell, or erythrocyte, possesses a most unusual cell shape. The discoid form, together with a distinctive red colouration, makes it one of the most easily recognised cell types in the body. It is also probably the most studied cell.
P. J. Winterburn +4 more
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The red blood cell, or erythrocyte, possesses a most unusual cell shape. The discoid form, together with a distinctive red colouration, makes it one of the most easily recognised cell types in the body. It is also probably the most studied cell.
P. J. Winterburn +4 more
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The Quality of Red Blood Cells
Immunological Investigations, 1995The evolving practice of medicine has required a number of changes in red cell product manufacture to ensure that the final product is more specifically tailored to the needs of the individual patient. As a result of the increasing concern over the risks of transfusion pharmaceutical standards of manufacture are now applied to blood component ...
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Red Blood Cell ATP Release Correlates with Red Blood Cell Hemolysis
The FASEB Journal, 2017The elegant and precise matching of blood flow to skeletal muscle from the onset of exercise through the steady state remains an important area of investigation. Release of adenosine triphosphate (ATP) from the red blood cell (RBC) has been postulated as a mediator of peripheral vascular tone in response to shear stress, hypoxia, and mechanical ...
Brian S. Ferguson +5 more
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Transfusion, 1973
A method used to increase the utilization of packed red blood cells and components is described. This required the staff of the blood center to visit hospital staff meetings and explain the use of platelet concentrates, cryoprecipitates, fresh frozen plasma, leukocyte‐poor blood, and packed red blood cells.
Richard H. Aster, G. A. Becker
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A method used to increase the utilization of packed red blood cells and components is described. This required the staff of the blood center to visit hospital staff meetings and explain the use of platelet concentrates, cryoprecipitates, fresh frozen plasma, leukocyte‐poor blood, and packed red blood cells.
Richard H. Aster, G. A. Becker
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JAMA: The Journal of the American Medical Association, 1970
To the Editor.— It is difficult for me to lend allegiance to the conclusions presented by the AMA Committee on Transfusion and Transplantation in the editorial published inThe Journal( 212 :147, 1970). Specifically, transfusion of red blood cells (RBC) rather than whole blood would certainly provide additional safety in the case of a patient who has ...
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To the Editor.— It is difficult for me to lend allegiance to the conclusions presented by the AMA Committee on Transfusion and Transplantation in the editorial published inThe Journal( 212 :147, 1970). Specifically, transfusion of red blood cells (RBC) rather than whole blood would certainly provide additional safety in the case of a patient who has ...
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Red blood cell rheology in sepsis
Intensive Care Medicine, 2003Changes in red blood cell (RBC) function can contribute to alterations in microcirculatory blood flow and cellular dysoxia in sepsis. Decreases in RBC and neutrophil deformability impair the passage of these cells through the microcirculation. While the role of leukocytes has been the focus of many studies in sepsis, the role of erythrocyte rheological
Piagnerelli, Michaël +3 more
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Cryopreserved red blood cells are superior to standard liquid red blood cells
Journal of Trauma and Acute Care Surgery, 2014Liquid preserved packed red blood cell (LPRBC) transfusions are used to treat anemia and increase end-organ perfusion. Throughout their storage duration, LPRBCs undergo biochemical and structural changes collectively known as the storage lesion. These changes adversely affect perfusion and oxygen off-loading.
Jerome A. Differding +8 more
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1977
The lipid in the mature erythrocyte of mammalian animals is solely contained in the plasma membrane. Lipids account for nearly 50% of the mass of the membrane while proteins are also present in a similar amount. Only very small quantities of sugars in the form of glycoproteins and glycolipids are present although these more hydrophilic moieties may be ...
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The lipid in the mature erythrocyte of mammalian animals is solely contained in the plasma membrane. Lipids account for nearly 50% of the mass of the membrane while proteins are also present in a similar amount. Only very small quantities of sugars in the form of glycoproteins and glycolipids are present although these more hydrophilic moieties may be ...
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Red blood cell deformability and protein adsorption on red blood cell surface
American Journal of Physiology-Heart and Circulatory Physiology, 1984Effects of protein and NaCl concentrations in plasma on red blood cell (RBC) deformability were studied using fresh human blood and a 5-microns Nuclepore filtration test. The protein and salt concentrations were varied by diluting the plasma with saline and adding crystalline NaCl to the fluids, respectively.
T. Koyama, Y. Kikuchi
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