Results 41 to 50 of about 345,987 (305)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Study to compare hematological parameters in alcoholic and non-alcoholic individuals

National Journal of Physiology, Pharmacy and Pharmacology, 2019
Background: Alcoholism represents one of the most serious worldwide socioeconomic health problems. It is one of the leading causes of preventable mortality, second only to cigarette smoking.
Akshay Berad, Vishakha Chand
doaj   +1 more source

Nucleated red blood cell count at birth as an index of perinatal brain damage

, 1999
OBJECTIVE: The prognostic value of the nucleated red blood cell count at birth with respect to perinatal brain damage and neonatal outcome was assessed in infants at high risk of having neurologic damage.
MASSAFRA, C., GIOIA, D., AGOSTA, R., PERRONE, S., BUONOCORE, G., GATTI, M. G., BRACCI, R.   +6 more
core   +1 more source

Multimedia teaching methodology in hematology practices: blood cell count using Neubauer chamber [PDF]

, 2022
[EN] Blood cell count is a technique widely used both in clinical and in research, and is essential in the area of health in order to identify the presence of hematological alterations.
Pineda Merlo, Begoña, Piqueras Franco, Marta, Lloret Alcañiz, Ana, Obrador Pla, Elena, Pascual Mora, Maria   +4 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Concentration of white blood cells from whole blood by dual centrifugo-pneumatic siphoning with density gradient medium [PDF]

, 2012
Due to the pervasiveness of HIV infections in developing countries there exists a need for a low-cost, user-friendly point-of-care device which can be used to monitor the concentration of T-lymphocytes in the patient’s blood expressing the CD4+ epitope ...
Glynn, Macdara, Kearney, Sinéad M., Ducrée, Jens, Kinahan, David J.   +3 more
core  

IdentiCyte: Simple red blood cell identification software [PDF]

, 2019
Counting and identifying red blood cells (RBCs) by shape is an important step in diagnosing several diseases and disorders. This is traditionally done by hand (a tedious and time consuming process) or with specialized equipment. There exist several tools
Giri, Saveen, Gil Garnier, Garnier, Guillaume F.G., Manderson, Clare A., Saveen Giri, Garnier, Gil, Clare A. Manderson, Guillaume F.G. Garnier   +7 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Complete blood cell count components and coronary slow-flow phenomenon

Therapeutics and Clinical Risk Management, 2016
Nasim Arjmand, Mohammad Reza Dehghani Department of Cardiology, Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, IranDespite the implementation of preventive strategies, ischemic heart disease and stroke remain the main ...
Arjmand N, Dehghani MR
doaj