Results 81 to 90 of about 345,987 (305)

Laboratory analyses for evaluation of platelet disorders and platelet concentrates

, 2006
High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core  

Changes in complete blood count parameters influenced by endocrine disorders

, 2021
Complete blood count is one of the most common diagnostic methods used in everyday practice. Hormonal status is known to affect blood count parameters.
Dadej, Daniela; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Kosicka, Weronika; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Szczepanek-Parulska, Ewelina; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Adamska, Martyna; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Krygier, Aleksandra; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Tuzimek, Dominika; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Skowrońska, Dagmara; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Świejkowska, Anna; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Ruchała, Marek; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland, Korda, Oliwia; Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland   +9 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Risk factors for trapped temporal horn formation during the treatment of central nervous system infections in neurosurgical patients

BMC Neurology
Objectives To investigate the potential risk factors associated with the formation of trapped temporal horn (TTH) during the treatment of central nervous system (CNS) infections in neurosurgical patients.
Wenkai Cong, Guanghong Qi, Shengjie Wang, Zhenwei Bai, Guangming Zhang, Biao Li, Mingda Zhang, Hongwei Chen   +7 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Red blood cell count as an indicator of microvascular complications in Chinese patients with type 2 diabetes mellitus

Vascular Health and Risk Management, 2013
Zhan-Sheng Wang,1,2 Zhan-Chun Song,1 Jing-Hui Bai,1 Fei Li,3 Tao Wu,1 Ji Qi,2 Jian Hu11Department of Cardiology, First Affiliated Hospital of China Medical University, 2Second Department of Cardiology, Fourth People's Hospital of Shenyang, Shenyang ...
Wang ZS, Song ZC, Bai JH, Li F, Wu T, Qi J, Hu J   +6 more
doaj  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Importance of haemogram parameters for prediction of the time of birth in women diagnosed with threatened preterm labour

Journal of International Medical Research, 2020
Objective This study aimed to estimate the importance of complete blood count parameters for predicting the timing of birth in threatened preterm labour cases.
Harun Egemen Tolunay, Erkan Elci
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source