Results 131 to 140 of about 60,471 (306)
Gaia-ESO survey: Lithium abundances in open cluster Red Clump stars
L. Magrini +27 more
openalex +1 more source
I determine a distance to the Fornax dwarf galaxy using stars in the red clump and at the tip of the red giant branch. They are in very good agreement, with $ _0 = 20.66 mag$. Comparing the magnitudes of the tip of the red giant branch and of the red clump in Fornax, Carina and the Magellanic Clouds, I propose a possible solution to the problem of the
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The possibility of applying photometry from the 2MASS J, H, Ks, MegaCam u, g and IPHAS r, i, Hα surveys for determining the distance to the dark cloud LDN1525 (TGU 1192) in the direction of the Aur OB1 association is investigated using the red clump ...
Straižys V., Drew J. E., Laugalys V.
doaj +1 more source
LARGE MAGELLANIC CLOUD DISTANCE AND STRUCTURE FROM NEAR-INFRARED RED CLUMP OBSERVATIONS [PDF]
Joel F. Koerwer
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
We present new measurements of the 2D geometry of the LMC’s stellar bar with precise astrometric observations of red clump stars in Gaia DR3. We develop a novel solution to tackle crowding-induced incompleteness in Gaia data sets with the Gaia BP-RP ...
Himansh Rathore +3 more
doaj +1 more source
A new photometric model of the Galactic bar using red clump giants [PDF]
Liang Cao +4 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

