Results 131 to 140 of about 60,471 (306)

Gaia-ESO survey: Lithium abundances in open cluster Red Clump stars

open access: green, 2021
L. Magrini   +27 more
openalex   +1 more source

The Distance to the Fornax Dwarf Galaxy Using Red Clump Stars and the Discrepancy between Red Clump and Tip of the Red Giant Branch Distances

open access: yesThe Astrophysical Journal, 2000
I determine a distance to the Fornax dwarf galaxy using stars in the red clump and at the tip of the red giant branch. They are in very good agreement, with $ _0 = 20.66 mag$. Comparing the magnitudes of the tip of the red giant branch and of the red clump in Fornax, Carina and the Magellanic Clouds, I propose a possible solution to the problem of the
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Extinctions and Distances to Dark Clouds from 2MASS, MegaCam and IPHAS Surveys: LDN 1525 in the Direction of the Aur OB1 Association

open access: yesOpen Astronomy, 2010
The possibility of applying photometry from the 2MASS J, H, Ks, MegaCam u, g and IPHAS r, i, Hα surveys for determining the distance to the dark cloud LDN1525 (TGU 1192) in the direction of the Aur OB1 association is investigated using the red clump ...
Straižys V., Drew J. E., Laugalys V.
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Precise Measurements of the LMC Bar’s Geometry with Gaia DR3 and a Novel Solution to Crowding-induced Incompleteness in Star Counting

open access: yesThe Astrophysical Journal
We present new measurements of the 2D geometry of the LMC’s stellar bar with precise astrometric observations of red clump stars in Gaia DR3. We develop a novel solution to tackle crowding-induced incompleteness in Gaia data sets with the Gaia BP-RP ...
Himansh Rathore   +3 more
doaj   +1 more source

A new photometric model of the Galactic bar using red clump giants [PDF]

open access: green, 2013
Liang Cao   +4 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

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