Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Discovery of a high-velocity cloud of the Milky Way as a potential dark galaxy. [PDF]
Liu XL +8 more
europepmc +1 more source
The morphology of the sub-giant branch and red clump reveal no sign of age spreads in intermediate-age clusters [PDF]
N. Bastian, Florian Niederhofer
openalex +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
SWI/SNF complexes modulate gene expression and the development of physical dependence to ethanol. [PDF]
Mathies LD +3 more
europepmc +1 more source
Assembling the Milky Way bulge from globular clusters: Evidence from the double red clump
Young‐Wook Lee +3 more
openalex +2 more sources
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Chain formation mediated by Escherichia coli immunoglobulin-binding proteins EibD and EibG depends on expression levels and localization of proteins. [PDF]
Swiatek LS, Schaufler K, Leo JC.
europepmc +1 more source
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Pattern formation along signaling gradients driven by active droplet behavior of cell swarms. [PDF]
Ford HZ +8 more
europepmc +1 more source

