Results 71 to 80 of about 1,925,617 (316)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Personality Red Flags of Fraud

Society
The persistent issue of substantial losses due to fraud has heightened interest in exploring factors contributing to fraudulent behavior, with limited focus on the role of personality traits in fraud detection.
Putu Wenny Saitri, Ni Putu Yuria Mendra, Ni Luh Gde Novitasari   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

PENGARUH PENGALAMAN, DAN SKEPTISME BAGI AUDITOR DI DALAM MENDETEKSI ADANYA RED FLAGS PADA SUATU TINDAK KECURANGAN LAPORAN KEUANGAN

Jurnal Akuntansi Kontemporer, 2020
Auditor as an independent party has an obligation to examine the company’s financial statements and stated that the fi-nancial statements are reasonable, but in carrying out the duties required expertise to identify the presence or absence of red flags ...
Gunawan Lesmana, Bintang Hari Yudhianti, S, Patricia Febrina Dwijayanti   +2 more
doaj   +1 more source

Non-specific low back pain: principles and algorithms for successful management of patients in real clinical practice

Неврология, нейропсихиатрия, психосоматика, 2023
Non-specific low back pain (LBP) occurs in most people at least once in a lifetime. In city polyclinics, every fourth patient complains of LBP. During the COVID-19 pandemic, the prevalence of acute non-specific LBP and chronic LBP have increased due to ...
V. A. Golovacheva, G. R. Tabeeva, A. A. Golovacheva   +2 more
doaj   +1 more source

Content analysis of XBRL filings as an efficient supplement of bankruptcy prediction? Empirical evidence based on US GAAP annual reports [PDF]

, 2012
Most of the bankruptcy prediction models developed so far have in common that they are based on quantitative data or more precisely financial ratios. However, useful information can be lost when disregarding soft information.
Henselmann, Klaus, Scherr, Elisabeth
core  

HadISD: a quality-controlled global synoptic report database for selected variables at long-term stations from 1973--2011 [PDF]

, 2012
[Abridged] This paper describes the creation of HadISD: an automatically quality-controlled synoptic resolution dataset of temperature, dewpoint temperature, sea-level pressure, wind speed, wind direction and cloud cover from global weather stations for ...
Dai, Aiguo, Dunn, Robert J. H., Durre, Imke, Parker, David E., Thorne, Peter W., Vose, Russ E., Willett, Kate M., Woolley, Emma V.   +7 more
core   +4 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

The clinical utility of routine spinal radiographs by chiropractors: a rapid review of the literature

Chiropractic & Manual Therapies, 2020
Introduction When indicated by signs or symptoms of potentially serious underlying pathology (red flags), chiropractors can use radiographs to inform their diagnosis.
Melissa Corso, Carol Cancelliere, Silvano Mior, Varsha Kumar, Ali Smith, Pierre Côté   +5 more
doaj   +1 more source

Nerve ultrasound in hereditary transthyretin amyloidosis: red flags and possible progression biomarkers

Journal of Neurology, 2020
Background Diagnostic delay of hereditary transthyretin amyloidosis (ATTRv, v for variant) prevents timely treatment and, therefore, concurs to the mortality of the disease.
A. Salvalaggio, D. Coraci, M. Cacciavillani, L. Obici, A. Mazzeo, M. Luigetti, F. Pastorelli, M. Grandis, T. Cavallaro, G. Bisogni, A. Lozza, C. Gemelli, L. Gentile, M. Ermani, G. Fabrizi, R. Plasmati, M. Campagnolo, F. Castellani, R. Gasparotti, C. Martinoli, L. Padua, C. Briani   +21 more
semanticscholar   +1 more source