Results 201 to 210 of about 562,012 (337)

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

Biomechanical limits of hopping in the hindlimbs of giant extinct kangaroos. [PDF]

Sci Rep
Jones ME, Jones K, Nudds RL.
europepmc   +1 more source

ABUNDANCES OF RED GIANTS IN OLD OPEN CLUSTERS. IV. NGC 1817, NGC 1883, NGC 2141, AND NGC 2158 [PDF]

, 2009
Heather R. Jacobson, Eileen D. Friel, C. A. Pilachowski   +2 more
openalex   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

The assembly of microbial communities on red sandstone surfaces was shaped by dispersal limitation and heterogeneous selection. [PDF]

mSystems
Wang B, Zhu C, Wang X, Yang T, Zhang B, Hu Y.   +5 more
europepmc   +1 more source

The Tip of the Red Giant Branch Distance Ladder and the Hubble Constant [PDF]

Siyang Li, Rachael L. Beaton
openalex   +1 more source

Proper motion dispersions of red clump giants in the galactic bulge: observations and model comparisons [PDF]

, 2007
Nicholas J. Rattenbury, Shude Mao, Victor P. Debattista, Takahiro Sumi, Ortwin Gerhard, Flavio De Lorenzi   +5 more
openalex   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

Advanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang, Xinyu Mao, Yu He, Qingshen Jia, Yiding Zhao, Xiaomeng Dai, Xiaoyan Li, Shengyi Sun, Xiaoyan Sheng, Dan Ding, Yuan Shi, Qian Gao, Ling Shuai   +12 more
wiley   +1 more source

Computational fluid dynamics analysis of hemodynamics in bicuspid aortic valve with giant aneurysm. [PDF]

J Cardiothorac Surg
Qiao Z, Dong W, Zhu S, Chen S, Chen Z, Zhang N, Chen D, Mao P, Zheng T, Zhu J.   +9 more
europepmc   +1 more source

Two’s a crowd? Characterising the effect of photometric contamination on the extraction of the global asteroseismic parameter ν_max in red-giant binaries [PDF]

, 2019
S. Sekaran, C. Johnston, A. Tkachenko, P. G. Beck, A. Prša, K. M. Hambleton   +5 more
openalex   +1 more source