Results 261 to 270 of about 550,992 (335)

Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex

open access: yesAdvanced Science, EarlyView.
The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua   +12 more
wiley   +1 more source

Temperature Thresholds Govern Microbial‐Mediated Dissolved Organic Carbon Dynamics in Coastal Ecosystems

open access: yesAdvanced Science, EarlyView.
Coastal dissolved organic carbon (DOC) represents one of the largest reduced carbon pools on Earth, and they are influenced by temperature. Across 7.6–35.9 °C ranges, the microbial‐mediated DOC dynamics is characterized by three temperature thresholds.
Junfu Dong   +12 more
wiley   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Bifacially Engineered Perovskite‐Based Synaptic Memristors Achieve High Linearity and Symmetricity for Accurate and Robust Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
Bifacially engineering metal halide perovskite‐based memristors using phenylethylammonium iodide without oxide layers concurrently achieves high linearity, symmetricity, and reliability—essential for analog neuromorphic computing. The devices exhibit enhanced synaptic behavior, a high on/off ratio of 3.67 × 105, and exceptional endurance exceeding 11 ...
Jang Woo Lee   +15 more
wiley   +1 more source

Adaptive changes in the intestinal microbiota of giant pandas following reintroduction. [PDF]

open access: yesSci Rep
Ma R   +15 more
europepmc   +1 more source

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