Cytotoxic activity of marine derived bioactive compounds from red sea sponges supported by LC-MS/MS profiling and molecular docking. [PDF]
Ibrahim NE +6 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Decoding microbial diversity, biogeochemical functions, and interaction potentials in red sea hydrothermal vents. [PDF]
Altalhi S +10 more
europepmc +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Genetic Divergence and Isolation of the Green Sea Turtle (<i>Chelonia mydas</i>) in the Red Sea. [PDF]
Scott K +10 more
europepmc +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Heteronemin and Other Cytotoxic Compounds from the Red Sea Sponge <i>Hyrtios erectus</i>: Isolation, Characterization, and Lipid Nanoparticle Formulation for Improved Cancer Therapy. [PDF]
El-Gamal AA +11 more
europepmc +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Doctors' knowledge, attitudes, and practices in managing dengue fever amid war: A study in three governmental hospitals in Port Sudan, Red Sea State, Sudan (2024). [PDF]
Ebrahim T +3 more
europepmc +1 more source

