Results 221 to 230 of about 5,746,488 (258)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation. [PDF]

Adv Sci (Weinh)
Liu R, Yuan X, He Z, Jin H, Tian J, Chen C, Liu Y, Zhang X, Wen S, Kropff E, Miao C.   +10 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Solar Doppler Velocity Results from the SDO EVE Level 4 Lines Data Product. [PDF]

Sol Phys
Woods TN, Chamberlin PC, Crotser D, Jones A, Borelli R, Woodraska D, Gonzalez G.   +6 more
europepmc   +1 more source

The nutritional and metabolic impact of night shift work in a real-world setting. [PDF]

NPJ Biol Timing Sleep
Jassil FC, Phillips NE, Hemmer A, Joris C, Biancolin AD, Hartmeyer SL, Dorribo V, Perrig S, Genton L, Sterpenich V, Salathé M, Pralong JA, Andersen M, Pichard C, Dibner C, Collet TH.   +15 more
europepmc   +1 more source

Standardized Spectral Mapping With ¹²⁹Xe Chemical Shift Imaging: Investigating Red Blood Cell Shift Heterogeneity in Pulmonary Hypertension. [PDF]

NMR Biomed
Costelle A, Leewiwatwong S, Mugler JP, Mummy D, Rajagopal S, Driehuys B.   +5 more
europepmc   +1 more source

Onsite DADQs-assisted chemiluminescence wavelength shift from luminol µPADs to tetracyanoquinodimethane-based fluorophores enabling sensitised emission of AuNPs in point-of-source testing (PoST) multimode device. [PDF]

RSC Adv
Mohitkar AS, Kumar PS, Sinha R, Mishra S, Goel S, Jayanty S.   +5 more
europepmc   +1 more source

Strategies towards designing visible and near-infrared light driven molecular motors.

Chem Soc Rev
Tu Y, Danowski W, Stindt CN, Sheng J, Feringa BL.   +4 more
europepmc   +1 more source