Results 181 to 190 of about 407,327 (266)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Social valence dictates sex differences in identity recognition. [PDF]

Transl Psychiatry
Larosa A, Xu QW, Yaghoubi M, Wong BW, Wong AS, Lee JQ, Brandon MP, Wong TP.   +7 more
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Current situation and influencing factors of scientific literacy in fitness of Chinese children and adolescents. [PDF]

Front Public Health
Zhang Y, Zhao D, Chen X, Chen J, Wang C, Li S, Naito H, Deng P.   +7 more
europepmc   +1 more source

MeeTeam, tu red social deportiva

, 2018
¿Cómo surge MeeTeam? Partiendo de mis propias vivencias durante más de 10 años en el mundo del fútbol sala y de las de muchas personas más, y siendo miembro fundador de un equipo y jugador, siempre nos hemos encontrado con los mismos dos problemas: - Encontrar jugadores y/o entrenadores para completar la plantilla. - Encontrar
openaire   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

State-Dependent and Social Modulation of Circulating Glucocorticoids in a Nomadic Songbird, the Red Crossbill (<i>Loxia Curvirostra</i>). [PDF]

Integr Org Biol
Vernasco BJ, Moore IT, Cornelius JM, Watts HE.   +3 more
europepmc   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

VR-CARE: a protocol for a mixed-methods study and pilot trial with embedded process evaluation to develop and evaluate virtual reality training for risk reduction in care homes. [PDF]

BMJ Open
Gasteiger N, Ford CR, Hawley-Hague H, Wilkinson J, Jones D, Whittaker W, Ullah A, Kislov R, Stanmore E, Laverty L, Chantrell J, Callaghan C, Edmondson V, Dowding D.   +13 more
europepmc   +1 more source