Results 31 to 40 of about 407,327 (266)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Twitter y poesía no creativa por Karen Villeda y Denise Audirac en su obra POETuitéame
Literatura Mexicana, 2019 El presente artículo estudia la obra de poesía digital POETuitéame de las autoras mexicanas Karen Villeda y Denise Audirac desde las teorías del arte conceptual y la escritura no creativa desarrolladas por Kenneth Goldsmith y la apropiación y ...
Daniel Escandell Montiel
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Uso de redes sociales en estudiantes de Promoción de la Salud en la era de la COVID-19
Revista Peruana de Ciencias de la Salud, 2021 Objetivo. El objetivo del artículo es describir el uso de las redes sociales (TikTok y Twitter) en estudiantes de medicina de una universidad privada peruana como parte de la actividad grupal de la primera evaluación de la asignatura de Promoción de ...
Elizabeth Espinoza-Portilla +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
La red territorial: una oportunidad para compartir la educación en comunidad
Educar, 2010 En este artículo se describen dos experiencias de redes sociales territoriales como propuesta metodológica que invita a la participación y al trabajo conjunto de la comunidad y busca caminos hacia la corresponsabilidad. Si bien cada red territorial tiene
Marta Amela +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
HISTOReLo: Revista de Historia Regional y Local, 2016 Las dinámicas sociales en Pamplona de Indias, provincia del Virreinato de Nueva Granada, a finales del siglo XVIII y comienzos del XIX, muestran el ascenso y consolidación del grupo conformado por hacendados-comerciantes insertos en el circuito ...
Lina Constanza Díaz Boada
doaj +1 more source