Results 51 to 60 of about 3,297,358 (361)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
HISTOReLo: Revista de Historia Regional y Local, 2016 Las dinámicas sociales en Pamplona de Indias, provincia del Virreinato de Nueva Granada, a finales del siglo XVIII y comienzos del XIX, muestran el ascenso y consolidación del grupo conformado por hacendados-comerciantes insertos en el circuito ...
Lina Constanza Díaz Boada
doaj +1 more source
Indigenous universities and the construction of interculturality: the case of the Peasant and Indigenous University Network in Yucatan, Mexico [PDF]
, 2010 “Interculturality” has become a key concept in the conceptualising and struggling for new relationships between dominant and subordinated identities and knowledges in Latin America.
Llanes Ortiz, Genner de Jesús
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
La televisión conectada: ventajas e inconvenientes del estándar HbbTV
Cuadernos.info, 2012 El fenómeno de asimilación e interacción entre televisión e Internet está creciendo de forma significativa en los últimos años. Eso se está traduciendo en un impulso en la penetración de la televisión conectada e híbrida, hasta el punto de la irrupción ...
JOAN FRANCESC FONDEVILA GASCÓN
doaj
Ciencia y Sociedad, 2017 El objetivo del presente estudio es conocer en qué medida el capital social y las redes sociales influyen en el desarrollo de la actitud emprendedora de los estudiantes, para lo cual se tomó una muestra de 92 sujetos que estudian diversas carreras y ...
José Feliz Marrero
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
La incursión del Congreso Nacional de Cirugía de Colombia en la red social Twitter™
Revista Colombiana de Cirugía, 2019 Introducción. Hemos ingresado en una nueva era en la forma de comunicación y en la difusión de los contenidos que se generan en las diferentes reuniones y congresos científicos de Medicina y Cirugía. Objetivo.
Diego Sierra Barbosa +4 more
doaj +1 more source