Results 61 to 70 of about 3,297,358 (361)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Etnopaisaje, turismo y ocio en la ciudad de Oporto. Un estudio exploratorio en Instagram [PDF]
Instagram es una de las red sociales de internet más importantes del mundo para compartir fotografías y vídeos. Es una plataforma usada cada vez más por empresas y otros actores turísticos en la promoción de destinos turísticos.
Fernando Manuel Rocha da Cruz
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Virtualización organizacional, Web semántica y redes sociales
La información ha estado presente en todas las comunidades y en todas las épocas; sin embargo, hoy la productividad y el poder tienen como base las tecnologías de gestión de la información, del conocimiento y de la comunicación de símbolos.
Carlos H. Caicedo E.
doaj
Audiencias televisivas y líderes de opinión en Twitter. Caso de estudio: El Barco
Este artículo presenta los resultados de una medición de flujo de tweets y su análisis posterior. Seguimos los modelos de predicción política ya utilizados para las campañas electorales por investigadores y autores previos. Proponemos también un análisis
Luis Deltell Escolar +2 more
doaj +1 more source
Observations of red-giant variable stars by Aboriginal Australians
Aboriginal Australians carefully observe the properties and positions of stars, including both overt and subtle changes in their brightness, for subsistence and social application. These observations are encoded in oral tradition.
Allen R. H. +48 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
PERBANDINGAN MODAL SOSIAL ANGGOTA DI DUA KELOMPOK TANI (Studi Kasus Kelompok Tani Teratai Merah Dan Kelompok Tani Teratai Putih) [PDF]
Social capital has an important role in achieving the goals of farmer groups. Each member of a farmer group has different social capital, even though the farmer group is in the same area.
Hasan, Juhan Mahdum
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

