Results 61 to 70 of about 2,154 (165)

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Minimal Evidence of Inflammaging in Naturalistic Chimpanzee Populations

American Journal of Biological Anthropology, Volume 189, Issue 2, February 2026.
ABSTRACT Objectives Whereas chronic inflammation is a hallmark of aging in many human populations, inflammaging is reduced in groups characterized by frequent physical activity and diets low in processed foods. Since most biomarkers of inflammation require blood sampling, comparative data from our closest primate relatives have been derived from ...
Megan F. Cole, Melissa Emery Thompson, Nicole Thompson González, Eleanor Paskus, Joshua Rukundo, Rebeca Atencia, Alexandra G. Rosati   +6 more
wiley   +1 more source

Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Microglia are macrophage‐like brain resident immune cells known to express numerous Alzheimer's disease risk genes. Here we generated a human induced pluripotent stem cell (iPSC) derived microglia cell culture model for use in neuroimmune modeling and therapeutic testing.
Angela K. Haskell, Joshua A. Kulas, William E. Carter, June Javens‐Wolfe, Raven Dance Hinkel, Mustapha Moussaif, Jacob S. Smiley, Olivia Lazaro, Sylvia Robertson, Alan D. Palkowitz, Bruce T. Lamb, Timothy I. Richardson, Jeffrey L. Dage, Shaoyou Chu, Travis Johnson, Louis F. Stancato, Abdul Qadir Syed   +16 more
wiley   +1 more source

Transformaciones urbanísticas en el área de influencia de las variantes de la red nacional de carreteras. Una visión del desarrollo de concesiones en la red vial primaria en sectores suburbanos en ciudades colombianas. Caso: DEVINORTE – Variante de Cajicá

, 2021
diagramas, fotografías a color, mapas, tablas A través de los contratos de concesiones viales se han construido variantes para evitar las congestiones que se causan en algunos centros poblados. En el área de influencia de estas autovías se viene presentando un cambio en el uso y ocupación del suelo, ocasionando la aparición de desarrollos urbanos que ...
openaire   +1 more source

Combined Delivery of CuO Nanoparticles and HIF‐1α Inhibitor Acriflavine for Synergistic Local Treatment of Glioblastoma

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
Encapsulated acriflavine (ACF) and copper oxide nanoparticles (CuO NPs) are coreleased from coaxial nanofibers, producing synergistic antiglioblastoma multiforme effects. ACF suppresses the hypoxia‐inducible factor 1α pathway related to many downstream factors for tumor growth, while CuO NPs generate reactive oxygen species that assist cuproptosis ...
Daewoo Han, Iris S. Weitz, Hasan Slika, Betty Tyler, Andrew J. Steckl   +4 more
wiley   +1 more source

Clasificación de Puentes en Argentina para la Evaluación de su Vulnerabilidad Sísmica

Tecnología y Ciencia, 2018
Recientes progresos en los métodos de evaluación del riesgo sísmico han llevado al desarrollo de funciones de fragilidad para clases específicas de puentes. Como primera etapa, para la construcción de dichas Curvas de fragilidad para puentes en Argentina,
José A. Saracho, Gustavo A. Pérez, José R. Barlek, Oscar Dip, Eduardo A. Castelli   +4 more
doaj  

Sistema computacional de análisis de la vulnerabilidad en puentes de la red vial nacional en Colombia utilizando el modelo de jerarquización analítica

, 2018
Magíster en Infraestructura ...
Rodriguez Bayona, Jhonny Alexander, Celis Fonseca, Oscar Leonardo   +1 more
openaire   +1 more source

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

Glia, Volume 74, Issue 2, February 2026.
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips, Emily G. Thompson, Olivia Spead, Balaji G. Vijayakumar, Erica R. Kent, Sean J. Miller, Treasure Nwokeleme, Svetlana Vidensky, Mohamed Hassan Farah, Jeffrey D. Rothstein   +9 more
wiley   +1 more source

Experimental and Computational Raman and SERS Study of Acid Blue 113

Journal of Raman Spectroscopy, Volume 57, Issue 2, Page 239-254, February 2026.
The vibrational features of AB‐113 were investigated through experimental and theoretical analyses. SERS spectra showed enhanced responses under resonant excitation, especially at 532 and 632.8 nm, enabling identification limits as low as 1.0 × 10−8 mol L−1.
Thayla C. A. Coelho, Flávia C. Marques, Gustavo F. S. Andrade   +2 more
wiley   +1 more source

Acid‐Promoted ROMP of a Pyridine‐Fused Norbornene Toward Main‐Chain Cationic Polymers

Macromolecular Chemistry and Physics, Volume 227, Issue 3, 16 February 2026.
Cationic polymers are valuable materials for applications ranging from biomedicine to ion transport. We report the ROMP of pyrido[2,3‐b]norbornadiene, a pyridine‐fused norbornene monomer, under acidic conditions. Protonation with HCl suppresses deleterious pyridine–Ru coordination, enabling controlled polymerization to afford well‐defined polymers with
An Tran, Vaishak Bhat, Quentin Michaudel
wiley   +1 more source