Results 121 to 130 of about 36,305 (267)

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries, Alastair M. Kilpatrick, Kathleen M. Scullion, Rhona Aird, Lorraine Bruce, Maria Elena Candela, Tak Yung Man, Stuart J. Forbes, James W. Dear   +8 more
wiley   +1 more source

Recepción de la Teoría Crítica en América Latina: la constelación benjaminiana de marxismo y teología en Franz Hinkelammert

Franciscanum, 2012
The article analyzes the relation between theology and historical materialism in Franz Hinkelammert and Walter Benjamin. From the consideration of diverse writings of both philosophers, important points of meeting appear between them, particularly ...
Estela Fernández Nadal
doaj  

Risk of Bias Associated with Varying Sampling Strategies for External Comparator Cohorts for Single‐Arm Trials: Insights from Aggressive Lymphoma

Clinical Pharmacology &Therapeutics, EarlyView.
Marketing authorizations for oncology drugs are often based on single‐arm trials (SATs), and real‐world data‐based external comparator cohorts (ECCs) are increasingly explored to contextualize results. In retrospective studies, comparators may be identified by time of diagnosis but included based on time of relapse; such sampling strategies can ...
Mikkel Runason Simonsen, Shiva Leisner, Ahmed Ludvigsen Al‐Mashhadi, Laurids Østergaard Poulsen, Matthew Maurer, Lasse Hjort Jakobsen, Tarec Christoffer El‐Galaly   +6 more
wiley   +1 more source

Mental Health and Well‐Being Across the Eating Disorder Spectrum—From Milder Symptoms of Disordered Eating Behaviors to Diagnosed Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined differences in mental health and well‐being, risk behaviors, suicidality, and social functioning across a proposed eating disorder (ED) spectrum, ranging from no ED symptoms to clinically diagnosed EDs. Methods We examined 44,303 participants in the 18‐year follow‐up in the Danish National Birth Cohort (DNBC‐18 ...
Anne V. Aurup, Andrea Joensen, Else Marie Olsen, Nadia M. Mikkelsen, Stine Danielsen, Pernille Stemann Larsen, Katrine Strandberg‐Larsen   +6 more
wiley   +1 more source

Moral Redemption and Its Significance

Moral redemption in secular contexts is often analyzed in terms of nearby concepts like apology, reparation, reformation, forgiveness, and reconciliation.
Liu, Ying
core   +1 more source

Images of the Moral Order: (Im)Morality and Redemption in Daniel Defoe’s The Fortunes and Misfortunes of the Famous Moll Flanders

American and British Studies Annual, 2011
The article starts from investigating the human preoccupation with the role and importance of divine providence through the centuries, with special emphasis on eighteenth-century English images of providence and divine authority, while observing the way
Mihaela Culea
doaj  

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Prognostic impact of iron deficiency in new‐onset chronic heart failure: Danish Heart Failure Registry insights

ESC Heart Failure, Volume 12, Issue 2, Page 1346-1357, April 2025.
Abstract Aims Iron deficiency (ID) is prevalent in chronic heart failure (HF) but lacks a consensus definition. This study evaluates the prevalence and the prognostic impact of ID using different criteria on all‐cause and cardiovascular mortality, as well as first hospitalization for HF in patients with new‐onset chronic HF.
Abdullahi Ahmed Mohamed, Daniel Mølager Christensen, Milan Mohammad, Christian Torp‐Pedersen, Lars Køber, Emil Loldrup Fosbøl, Tor Biering‐Sørensen, Morten Lock Hansen, Mariam Elmegaard Malik, Nina Nouhravesh, Charlotte Anderrson, Morten Schou, Gunnar Gislason   +12 more
wiley   +1 more source

Predictors of Voucher Redemption in Produce Prescription Programs in a Primarily Low-Income Population With Type 2 Diabetes. [PDF]

Prev Chronic Dis
Adebile TV, Rutt K, Scartozzi C, Calo WA, Kraschnewski JL, Hollis-Hansen K, Veldheer S.   +6 more
europepmc   +1 more source

‘Working Through’ Interpersonal Transgressions: The Role of Narration (and Re‐Narration) in the Self‐Forgiveness Processes of Wrongdoers

European Journal of Social Psychology, EarlyView.
ABSTRACT This research examines how wrongdoers may use narration to ‘work through’ a transgression committed, towards self‐forgiveness and reconciliation. In Study 1 (N = 30), reflexive thematic analysis was used to identify narrative types observable in wrongdoers’ storying of a recent interpersonal transgression, informing our conceptual framework ...
Christiana Harous, Michael Wenzel, Lydia Woodyatt   +2 more
wiley   +1 more source