Results 221 to 230 of about 233,572 (268)

Is Saturation Biopsy Still a Viable Alternative to Fusion Biopsy in the Era of Multiparametric MRI? A Comparative Analysis in Patients With Prior Negative Biopsy

open access: yesThe Prostate, EarlyView.
ABSTRACT Background We aimed to compare the diagnostic accuracy of transrectal ultrasound (TRUS)‐guided saturation biopsy (SB) and multiparametric MRI (mpMRI)‐TRUS fusion‐guided combined biopsy (CB) in patients with prior negative prostate biopsies. Methods We retrospectively analyzed data from 160 patients who underwent transrectal prostate biopsy ...
Arda Taşkın Taşkıran   +1 more
wiley   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve   +6 more
wiley   +1 more source

Challenges in designing interventions for food insecure families with food allergy in a Californian latinx cohort. [PDF]

open access: yesFront Allergy
Albarran M   +6 more
europepmc   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Stethoscope and Motherhood. [PDF]

open access: yesJ Grad Med Educ
Shapoo N, Boma N.
europepmc   +1 more source

Phase I Multivariate Coefficient of Variation Control Charts for High‐Dimensional Processes

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT Multivariate control charts have traditionally focused on monitoring the process mean vector and/or covariance matrix. Recent studies have extended this framework to Phase II monitoring of the multivariate coefficient of variation (MCV); yet very limited work has examined MCV‐based monitoring in Phase I.
O. A. Oyegoke   +2 more
wiley   +1 more source

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