Results 111 to 120 of about 1,684,510 (297)
Hidden dimensions of governments. Executives as cohesive networks of power groups [PDF]
Esta comunicación presenta algunos resultados de un anàlisis de redes de dos ejecutivos españoles.Universidad de Málaga.
Villena Oliver, Andrés
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Explorando la formación y características de un sistema migratorio iberoamericano.
El artículo analiza la constitución de un sistema migratorio que vincula España, como receptor central, con países de Latinoamérica y el Caribe. El análisis se basó en fuentes estadísticas y ha demostrado que el sistema migratorio se encontraba ...
Fernando Osvaldo Esteban
doaj
Reciprocidade e redes sociais aplicadas a análise e a promoção de dinâmicas territoriais [PDF]
O trabalho trata do papel das redes sociais e institucionais para a promoção de políticas públicas nos territórios, notadamente na escala regional. São examinadas três teorias que integram a análise das redes sociais ou sócio técnicas para analisar ...
Sabourin, Eric
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
En un contexto de creciente plataformización de la ciudad donde los teléfonos móviles configuran una especie de prótesis-cuerpo-territorio, buscamos recuperar rastros de la historia cultural de los teléfonos públicos y recomponer elementos del proceso ...
Paula Vera
doaj

