Results 251 to 260 of about 2,230,467 (338)

Marketing violations involving products that compete with breastfeeding in the vicinity of early childhood education centers and health centers: a cross-sectional study based on an audit of the retail food environment, Maceió, 2022-2023. [PDF]

Epidemiol Serv Saude
Bastos ECL, Vidal NAC, Aragão LDS, Costa GMA, Silveira JACD.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Brazilian adaptation and validation of the Multidimensional Measure of Parasocial Relationships (MMPR). [PDF]

Sci Rep
da Costa Daniele TM, de Araújo Moura L, Sánchez-Villegas M, Björk E, Garcia D.   +4 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Application of the Respondent-Driven Sampling method in an online survey in Brazil: COVID-19 morbidity in the post-pandemic period. [PDF]

Rev Bras Epidemiol
Souza Júnior PRB, Damacena GN, Castilho EA, Almeida WDS, Gomes CS, Malta DC, Szwarcwald CL.   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Advanced artificial intelligence in piRNA and PIWI-like protein research: A systematic review of recurrent neural networks, long short-term memory, and emerging computational techniques [PDF]

Biomedica
Reyes JS, Guevara JD, Picón LT, Sánchez IL, Gaona LA, Montoya MP, Pino LE.   +6 more
europepmc   +1 more source

Posicionamento estratégico das redes de supermercados locais : um estudo na cidade de Santos

, 2008
Ricardo Pastore
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

From childhood trauma to complex PTSD: a network analysis. [PDF]

Eur J Psychotraumatol
Kim E, Ko YG.
europepmc   +1 more source