Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz +20 more
wiley +1 more source
[Intersubjectivity and modes of care in health: eco-ethno-social sensitivity and critical technological competence for quality-equity in digital health]. [PDF]
Almeida-Filho N, Ayres JRCM.
europepmc +1 more source
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang +7 more
wiley +1 more source
[Prevalence of electronic cigarette use and refill compositions among young people and adults in Cantabria]. [PDF]
Fernández-Carrillo PD +5 more
europepmc +1 more source
Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre +12 more
wiley +1 more source
Paving the Way to Elucidate Hg's Role in Tumorigenesis
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li +10 more
wiley +1 more source
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen +11 more
wiley +1 more source
Social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV: a scoping review. [PDF]
Piran CMG +7 more
europepmc +1 more source
This study delineates a novel HSP90AB1‐ITGBL1 signaling axis governing osteosarcoma. HSP90AB1 promotes K63‐linked ubiquitination and proteasomal degradation of ITGBL1. Restoring ITGBL1 induces reactive oxygen species‐dependent endoplasmic reticulum stress and pro‐death autophagy, suppressing tumor growth and metastasis.
Zhen Wang +17 more
wiley +1 more source
Factors associated with extensions and withdrawals from stricto sensu graduate programs in Brazil during the COVID-19 pandemic: emphasis on mental health. [PDF]
Teixeira LR +4 more
europepmc +1 more source

