Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar+10 more
wiley +1 more source
[What the World Health Organization teaches us about mental health in primary care]. [PDF]
Pérez García MDP+2 more
europepmc +1 more source
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong+12 more
wiley +1 more source
[Applications of artificial intelligence in science: a practical guide for editors and authors]. [PDF]
Tinoco-Mesquita C+4 more
europepmc +1 more source
A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang+8 more
wiley +1 more source
[Barriers and strategies for healthcare accessibility for trans people in Cordoba, Argentina]. [PDF]
Cordero ML, Saletti-Cuesta L.
europepmc +1 more source
Adaptación y fiabilidad del cuestionario de red social, versión española del "Questionario sulla rete sociale", aplicado a personas con trastorno mental severo. [PDF]
Pablo García-Cubillana+5 more
openalex
Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen+13 more
wiley +1 more source
[Perception of professionalism among Latin American physicians in 2024: A multi-national survey]. [PDF]
Real-Delor RE+11 more
europepmc +1 more source
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan+19 more
wiley +1 more source