Results 71 to 80 of about 415,074 (257)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Two-Dimensional DOA Estimation in Compressed Sensing with Compressive-Reduced Dimension-lp-MUSIC

International Journal of Antennas and Propagation, 2015
This paper presents a novel two-dimensional (2D) direction of arrival (DOA) estimation method in compressed sensing (CS) to remove the estimation failure problem and achieve superior performance. The proposed method separates the steering vector into two
Weijian Si, Xinggen Qu, Lutao Liu, Zhiyu Qu   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Beam-Space Post-Doppler Reduced-Dimension STAP Based on Sparse Bayesian Learning

Remote Sensing
The space–time adaptive processing (STAP) technique can effectively suppress the ground clutter faced by the airborne radar during its downward-looking operation and thus can significantly improve the detection performance of moving targets. However, the
Junxiang Cao, Tong Wang, Degen Wang
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Non-iterative coordinated dispatch of active distribution network with clustered flexible loads via dimension-reduced aggregation

International Journal of Electrical Power & Energy Systems
Flexible loads (FLs), as a massive flexibility resource of the demand side, are essential in enhancing the operational economics of the active distribution network (ADN).
Li Pan, Junyong Liu, Hongjun Gao, Jing Yan, Zao Tang, Jingxian Yang   +5 more
doaj   +1 more source

Evaluating the Role of the EOF Analysis in 4DEnVar Methods

Atmosphere, 2017
The four-dimensional variational data assimilation (4DVar) method is one of the most popular techniques used in numerical weather prediction. Nevertheless, the needs of the adjoint model and the linearization of the forecast model largely limit the wider
Xingxia Kou, Zhekun Huang, Hongnian Liu, Meigen Zhang, Si Shen, Zhen Peng   +5 more
doaj   +1 more source

Data‐dependent reduced‐dimension STAP

IET Radar, Sonar & Navigation, 2019
Space‐time adaptive processing (STAP) is supposed to be a key technique for detection of slow‐moving targets in airborne radar applications. To overcome the difficulties of obtaining lots of independent and identical distributed secondary data samples, many sub‐optimal STAP algorithms are proposed such as reduced‐dimension STAP, reduced‐rank STAP, or ...
Wei Zhang, Minghua Han, Zishu He, Huiyong Li   +3 more
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source