Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Stochastic Uncertainty Analysis of Integrated Blisk-Shaft Rotor Vibrations Using Artificial Neural Networks and Reduced-Order Models. [PDF]
Sun H, Li X, Bai X, Yuan H, Zhang H.
europepmc +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Optical Anisotropy as a Probe of Proton Ordering at Ice Surfaces. [PDF]
Muroni A +4 more
europepmc +1 more source
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Learning variable-order time fractional diffusion equations using Physics-Informed Neural Networks. [PDF]
Ren L, Jin S.
europepmc +1 more source
Comment on "Multidimensional kinetic study on the organocatalyzed ring-opening polymerization (ROP) of l-lactide <i>via</i> a robotic high-throughput flow platform" by B. Zhang and T. Junkers, <i>Chem. Sci.</i>, 2026, <b>17</b>, 4706. [PDF]
Clothier GKK, Harrisson S.
europepmc +1 more source
In vivo efficacy of current stimuli computed by optimal tracking of neuron membrane voltage. [PDF]
Ferguson AC +5 more
europepmc +1 more source
Systems modeling of a phenazine-producing Escherichia coli bio-battery anolyte. [PDF]
King SM, King MR.
europepmc +1 more source
Deep neural network model for fractional-order cancer chemotherapy dynamics. [PDF]
Shafqat R +3 more
europepmc +1 more source

