Results 161 to 170 of about 7,720,158 (325)
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Koopman Reduced-Order Modeling with Confidence Bounds
SIAM Journal on Applied Dynamical SystemsThis paper introduces a reduced order modeling technique based on Koopman operator theory that gives confidence bounds on the model's predictions. It is based on a data-driven spectral decomposition of the Koopman operator. The reduced order model is constructed using a finite number of Koopman eigenvalues and modes, while the rest of spectrum is ...
Mohr, Ryan +2 more
openaire +2 more sources
Recent Advances in reduced-order modeling of complex interconnects [PDF]
, 2001 Canavero, Flavio +2 more
core +1 more source
Pade-Type Model Reduction of Second-Order and Higher-Order Linear Dynamical Systems
, 2004 A standard approach to reduced-order modeling of higher-order linear dynamical systems is to rewrite the system as an equivalent first-order system and then employ Krylov-subspace techniques for reduced-order modeling of first-order systems.
Freund, Roland W.
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A sequential semidefinite programming method and an application in passive reduced-order modeling
, 2005 We consider the solution of nonlinear programs with nonlinear semidefiniteness constraints. The need for an efficient exploitation of the cone of positive semidefinite matrices makes the solution of such nonlinear semidefinite programs more complicated ...
Freund, Roland W. +2 more
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
A comparison of reduced-order techniques for complex interconnects modeling [PDF]
, 2002 Canavero, Flavio +3 more
core +1 more source
Active Flutter Suppression Using Reduced-Order Modeling for Transonic Aeroservoelastic Control Law Development [PDF]
In this paper, several aerodynamic reduced-order models (ROMs) are generated and coupled with structural models to form aeroelastic ROMs. The aerodynamic ROMs generated here include the effects of control surface motion and are appropriate for use in ...
Bartels, Robert E. +3 more
core +1 more source