Results 221 to 230 of about 16,498,605 (322)

Non-Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review. [PDF]

Fundam Clin Pharmacol
Mesquita MJTAM, da Cruz ACSN, de Abreu Lima R, Tenório-Meireles J, Farias AJN, Santos IN, Frota G, de Moura Carvalho TGP, Carvalho RAF, Meireles-Teixeira JA, Prazeres T, Carvalho RC, do Socorro de Sousa Cartágenes M, Garcia JBS.   +13 more
europepmc   +1 more source

The potential impact of conservation, alternative energy sources, and reduced nonenergy emissions on global warming

, 1989
Emma L. Aronson, M. W. Edenburn
openalex   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Total Bolus Transit Time Predicts Cardiac Dysfunction in Acute Ischemic Stroke and Transient Ischemic Attack Patients: A Retrospective Double Center Study. [PDF]

Eur J Neurol
Bellavia S, Rizzo PA, Scala I, Di Giovanni J, Meduri A, Broccolini A, Marca GD, Scalise S, Paladini A, Colò F, Gaudino S, Calabresi P, Caggiula M, Frisullo G.   +13 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Does Time Tick Faster in Cerebral Palsy? Accelerated Aging as a Framework for Skeletal Muscle Dysfunction. [PDF]

FASEB J
Horwath O, Edman S, Dayanidhi S, Englund D, Peterson MD, von Walden F.   +5 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Reduced- Compared with Standard-Dose Direct Oral Anticoagulant for Extended Treatment of Venous Thromboembolism: A Systematic Review and Meta-Analysis. [PDF]

TH Open
Cheung CKM, Carlin S, Scheier TC, Yi QL, Chan NC, Bhagirath V, Petropoulos JA, Wong R, Weitz JI, Eikelboom JW.   +9 more
europepmc   +1 more source

Reducing cholesterol does not reduce mortality

Journal of the American College of Cardiology, 1988
openaire   +2 more sources

Decision letter for "Simulation and experimental study on lubrication of high-speed reducer of electric vehicle"

, 2020

openalex   +1 more source