Results 131 to 140 of about 4,249,295 (316)

Generative adversarial reduced order modelling

Scientific Reports
AbstractIn this work, we present GAROM, a new approach for reduced order modeling (ROM) based on generative adversarial networks (GANs). GANs attempt to learn to generate data with the same statistics of the underlying distribution of a dataset, using two neural networks, namely discriminator and generator.
Coscia, Dario, Demo, Nicola, Rozza, Gianluigi   +2 more
openaire   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Dissipativity preserving model reduction by retention of trajectories of minimal dissipation [PDF]

, 2009
We present a method for model reduction based on ideas from the behavioral theory of dissipative systems, in which the reduced order model is required to reproduce a subset of the set of trajectories of minimal dissipation of the original system.
Paolo Rapisarda, Harry L. Trentelman, Trentelman, Harry L.,, Rapisarda, Paolo, Rapisarda, P., Minh, H B, Trentelman, H.L., Minh, Ha Binh,, Ha Binh Minh, [No Value], Rapisarda, Paolo,, Ha Binh Minh, Ha, B.M., Trentelman, Harry L.   +12 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Advanced System-Level Model Reduction Method for Multi-Converter DC Power Systems

CSEE Journal of Power and Energy Systems
For dynamic stability analysis and instability mechanism understanding of multi-converter medium voltage DC power systems with droop-based double-loop control, an advanced system-level model reduction method is proposed.
Lin Zhu, Xueshen Zhao, Xialin Li, Li Guo, Bo Zhao, Zhanfeng Deng, Hao Lu, Chengshan Wang   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Reduced order model for hard magnetic films

AIP Advances
In the pursuit of rare earth-lean permanent magnets for green technologies, microstructural optimisation offers a promising strategy to enhance coercivity while minimising critical element content.
H. Moustafa, A. Kovacs, J. Fischbacher, M. Gusenbauer, Q. Ali, L. Breth, Y. Hong, W. Rigaut, T. Devillers, N. M. Dempsey, T. Schrefl, H. Oezelt   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Reduced Order Model of the Thermal Profile of the Rolls for the Real-Time Control System

Energies
Effective real-time control systems require fast and accurate models. The thermal profile models of the rolls presented in this paper are proposed for a real-time control system for the design of the rolling schedule.
Dmytro Svyetlichnyy
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source