Results 111 to 120 of about 4,289,373 (226)
ObjectiveIn the fields of underwater vehicles and aerospace, ring-stiffened cylindrical shells are widely used. Achieving a refined design for such structures is crucial to reducing structural weight while meeting strength and stability requirements ...
Junyi WANG, Yuansheng CHENG
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
An Updated List of Species Used in Tree-Ring Research
During the past 100 years, researchers have investigated the potential of hundreds of tree and shrub species for use in applications of tree-ring research.
Grissino-Mayer, Henri D.
core +3 more sources
Selecting and Characterizing Tree-Ring Chronologies for Dendroclimatic Analysis
A widely spaced grid of tree-ring chronologies most suitable for dendroclimatic analysis of western North America is selected objectively on the basis of 1) numbers in the sample, length in years, and site locations, 2) statistical characteristics of the
Fritts, Harold C., Shatz, David J.
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
The International Tree-Ring Data Bank (ITRDB) is an invaluable resource, providing access to a massive and growing cache of tree-ring data. Oxygen, carbon, nitrogen and hydrogen isotope treering studies, which have provided valuable climatic and ...
Csank, Adam Z.
core +2 more sources
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

