Results 71 to 80 of about 4,018,839 (226)
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
ObjectiveThis paper seeks to investigate the vibration reduction characteristics of a spiral acoustic black hole (SABH) on a ring-stiffened cylindrical shell and provide a new technical approach for the vibration reduction design of ring-stiffened ...
Weihao WANG +5 more
doaj +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
On regular ideals in reduced rings
Let R be a commutative ring with identity and X be a Tychonoff space. An ideal I of R is Von Neumann regular (briefly, regular) if for every a ? I, there exists b ? R such that a = a2b. In the present paper, we obtain the general form of a regular ideal in C(X) which is OA, for some closed subset A of ?X, for which Ac?X ? (P(X))?, where P(X)
Aliabady, A. R. +2 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Long-term results of intrastromal ring implantation for keratoconus [PDF]
Objective: To evaluate refractive and topographic outcomes before and at least 7 years after intrastromal ring segment implantation surgery in patients with keratoconus.
Henrique Celso Duarte de Rezende Rocha +4 more
doaj +1 more source
On Residually Reducible Representations on Local Rings
Let \(A\) be a local Artinian ring with maximal ideal \(\mathcal M\), let \(R\) be an \(A\)-algebra and let \(\rho\) be an \(A\)-representation of \(R\). If the residual representation \(\overline\rho\) (that is, with values in the residue field) is absolutely irreducible, then it is well-known by a result of Carayol that \(\rho\) is completely ...
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
In our study we examine definition of strongly γ -regular rings and associates, investigate interplay between strongly γ - regular rings and other reduced rings. We also study GP – injective modules, and discuss its relation with strongly
Luma Ahmed Khaleel, Beyda S. Abdullah
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

