Results 91 to 100 of about 4,043,219 (290)
Given a domain of characteristic zero R , we functorially construct a rigid symmetric monoidal dg-category whose K_{0} is ...
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
$e$-Reduced rings in terms of the Zhou radical [PDF]
Let $R$ be a ring, $e$ an idempotent of $R$ and $\delta(R)$ denote the intersection of all essential maximal right ideals of $R$ which is called Zhou radical. In this paper, the Zhou radical of a ring is applied to the $e$-reduced property of rings.
Kose, Handan +2 more
core
Residual stress will be in the thin wall bearing rings after they are machined. The residual stress may change the organizational performance and dimension of the bearing rings, and reduce the rate of qualified products resulting in loss of product ...
X.M. Li
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Medium-Sized Ring Expansion Strategies: Enhancing Small-Molecule Library Development
The construction of a small molecule library that includes compounds with medium-sized rings is increasingly essential in drug discovery. These compounds are essential for identifying novel therapeutic agents capable of targeting “undruggable” targets ...
Hwiyeong Lee, Jonghoon Kim, Minseob Koh
doaj +1 more source
Bu tezde indirgenmiŞ halka ve modüller, Baer ve quasi Baer halka ve modüller ilea-indirgenmiş modüller çalışılmıştır.Çalışma temel olarak dört bölümden oluşmaktadır. Ilk bölümde, teze girişyapılmıştır.İkinci bölümde, halka ve modüller ile ilgili diğer bölümlerde kullanacağımız bazıtemel tanımlar ve özellikler verilmiştir.Üçüncü bölümde, indirgenmiş ve ...
openaire +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

